Tauopathy
| Tauopathy | |
|---|---|
| Specialty | Neurology  |
Tauopathies are a class of neurodegenerative diseases resulting from the pathological aggregation of tau protein[1] in so-called neurofibrillary tangles (NFT) in the human brain.
Some examples of tauopathies are:
- Alzheimer's disease (alternately classified as an amyloidosis)[2]
- Argyrophilic grain disease
- Frontotemporal dementia
- Progressive supranuclear palsy
- Corticobasal degeneration
- Frontotemporal lobar degeneration, also known as Pick's disease
The non-Alzheimer's tauopathies are sometimes grouped together as "Pick's complex". [3]
References
- ^ Rizzo G, Martinelli P, Manners D; et al. (2008). "Diffusion-weighted brain imaging study of patients with clinical diagnosis of corticobasal degeneration, progressive supranuclear palsy and Parkinson's disease". Brain. 131 (Pt 10): 2690–700. doi:10.1093/brain/awn195. PMID 18819991.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Dennis W. Dickson. International Journal of Clinical and Experimental Pathology. PMC 2776269. PMID 19918325 [Neuropathology of Non-Alzheimer Degenerative Disorders [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776269/?tool=pubmed Neuropathology of Non-Alzheimer Degenerative Disorders]].
{{cite journal}}: Check|url=value (help); Missing or empty|title=(help) - ^ Andrew Kertesz, MD, FRCPC (2003). Movement disorders:official journal of the movement disorder society. 18 (S6). PMID 14502657 [Pick's complex and FTDP-17 [http://www.ncbi.nlm.nih.gov/pubmed/14502657 Pick's complex and FTDP-17]].
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External links
http://www.lifesci.sussex.ac.uk/home/Julian_Thorpe/ad_cyto.htm#tau Proteopathy
- Luc Buée; André Delacourte (1999). Brain Pathology. 9: 681–693. PMID 10517507 [Comparative Biochemistry of Tau in Progressive Supranuclear Palsy, Corticobasal Degeneration, FTDP-17 and Pick’s Disease [http://pagesperso-orange.fr/alzheimer.lille/pdf/1999/1999BueeBrainPathol.pdf Comparative Biochemistry of Tau in Progressive Supranuclear Palsy, Corticobasal Degeneration, FTDP-17 and Pick’s Disease]].
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