Talk:Lorazepam

Pharmacology B‑class High‑importance

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Areas of Lorazepam article needing work:

Pharmacology: Basic mode of benzodiazepine action at receptor level, possibly with a diagram (may easily confuse rather than impart meaningful information).

Side effects: Question whether to paste in a complete list, as below, or just to leave readers to refer to official data sheets.

Dosages: may be wise to defer questions like this to official data sheets, but is there a bare minimum of representative examples?

Interactions: there is just the ethanol interaction at the moment.

Lay readers: I discussed article with a layperson, who found it overwhelming. It is a pharmacology article, but anything that conveys the same information in clearer English... --Petlif 21:54, 22 August 2007 (UTC)[reply]

A diagram of the GABAa receptor (being a six subunit ion channel in the plasma membrane) might muddle things for the reader - if they are unfamiliar with that particular class of receptor. Regardless, there needs to be more information regarding the affinity of Lorazepam for the receptor, where it binds, what subunits it possesses, stuff like that. The interactions section needs to be expanded to include barbituates and other drugs/chemicals which modulate the affinity of GABA. Wisdom89 23:34, 22 August 2007 (UTC)[reply]

Interactions

Anyone going to kick off in the section on Lorazepam drug interactions?