Evoxine

Evoxine
Clinical data
ATC code	none;
Legal status
Legal status	In general: legal;
Identifiers
	IUPAC name 1-(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol;
CAS Number	522-11-2;
PubChem CID	73416;
CompTox Dashboard (EPA)	DTXSID801028138 ;
Chemical and physical data
Formula	C11H12O2
Molar mass	347.362 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O;

Evoxine (Haploperine) is an alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides^[1] and Teclea gerrardii.^[2]

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References

^ Eastwood FW, Hughes GK, Ritchie E. Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine. Australian Journal of Chemistry. 1954; 7(1):87-98.
^ Waffo AF, Coombes PH, Crouch NR, Mulholland DA, El Amin SM, Smith PJ. Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa. Phytochemistry. 2007 Mar;68(5):663-7. PMID 17174364