Metis (World of Darkness)
Metis are a fictional breed of werewolves from the Werewolf: The Apocalypse role-playing game. They are heavily discriminated against, as they all are sterile and have a random deformity. Their natural state is that of the crinos form, making them very dangerous to sleep around.They are created from the pairing of two Garou, which is a break of the litiny, mainly because of the stigma of bearing a metis offspring.
The Children of Gaia are the only tribe that openly accepts all metis, a few others accept their own, notably the Bone Gnawers and Silent Striders.
There are some theories as to the nature of why metis are different, some point out that there is nothing medically wrong with their reproductive systems. So maybe Gaia has some bigger plan for them....