Janeway lesion
| Janeway lesion | |
|---|---|
| Specialty | Infectious diseases  |
Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are pathognomonic of infective endocarditis.[1] Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.[1] They are caused by septic emboli which deposit bacteria, forming microabscesses.[2] Janeway lesions are distal, flat, ecchymotic, and painless.
Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness.[3]
Eponym
They are named after Edward G. Janeway (1841–1911), an American professor of medicine with interests in cardiology and infectious disease.[4]
See also
References
- ^ a b Farrior, J.B. (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., Churchill Livingstone 2009.
- ^ Farrior JB, Silverman ME (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Janeway C. (1998). "Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response". J. Immunol. 161 (2): 539–44. PMID 9670925.
Supporting images
Template:Eponymous medical signs for circulatory and respiratory systems