Talk:Colchicine

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I have been prescribed this drug for a heart condition. Has anyone else been prescribed this drug for a similar condition.

Depends on a lot of things. If you have cardiac amyloidosis after chronic inflammation or familial Meditteranean fever, this sounds entirely appropriate. Otherwise, it is not normally used in heart disease. JFW | T@lk 02:35, 31 Dec 2004 (UTC)

Edits by Gzuckier

I like the edits recently done by Gzuckier, I think they add to ease of read. But I think they add a bit of redundancy and repitition to the affected sentence. The repeated bits (chromosome seperation) were originally added by me, but I prefer gzuckier's edit, but i don't feel worthy to fix the flow of the article, perhaps someone can step up to the plate?

Adenosine | Talk 02:11, July 14, 2005 (UTC)

Dangers

I recently was prescribed Cholchicine for FMF that I had for 20 years before any doctor could figure it out. However now that I take the pill everyday I am afraid that it could be causing detriments to my body. Any suggestions to counter them?

Colchicine is fairly safe and is used by gout sufferers on a regular basis. The main side-effects are listed. What exactly are you concerned about? JFW | T@lk 08:34, 29 March 2009 (UTC)[reply]

Blakeslee and Avery

[1] Samsara (talk • contribs) 02:22, 11 December 2006 (UTC)[reply]

Correction about use early in gout attack

I removed the sentence "Starting the drug early during an attack of gout can exacerbate the symptoms" because it's probably wrong:

1. There was no reference.

2. It's contrary to what I've heard and my experience.

3. See http://www.medscape.com/viewarticle/406509_6 and http://www.rheumatology.org/public/factsheets/gout_new.asp which say it's good in early gout.

4. Some other drugs such as Allopurinol are bad early in an attack which is possibly the source of the confusion.

5. I could be wrong and would be happy to read references saying that colchicine is bad in early gout.

Stevechelt 17:21, 11 January 2007 (UTC)[reply]

I would agree with the above -- in fact I begged my doctor to give me allopurinol in the start of my gout attack (after a break in medication due to various reasons). But he said that could cause a flare up and said this has to be taken. —Preceding unsigned comment added by 122.167.92.39 (talk) 16:17, 1 October 2007 (UTC)[reply]

Grammar/Syntax Correction

The reference to the IV colchicine that was implicated in patient deaths indicated that the preparation was 10 times as strong as indicated on the label. I edited the article to reflect that fact. Justus R 12:32, 2 July 2007 (UTC)[reply]

Colchicine as an FDA approved drug

I edited the text as Colchicine on its own is not FDA approved, it belongs to a group of drugs prescribed prior to FDA enforcement. I do know however that URL is submitting or have submitted a 505 b 2 application to the FDA for approval.

http://www.fda.gov/cder/drug/unapproved_drugs/industry.htm#unapproved_drugs_coordinator

TT—Preceding unsigned comment added by 64.9.100.40 (talk) 17:21, 19 February 2009 (UTC)[reply]

{{sofixit}} JFW | T@lk 08:34, 29 March 2009 (UTC)[reply]

Someone wrote that colchicine was a "generic drug for over 200 years." That is ridiculous. Generic drugs as we know them today have only existed since 1984, and drugs have only been approved since the FDCA in 1938 (this is US law). I amended the text accordingly. Also, colchicine was awarded orphan drug exclusivity for 7 years, not 3 years as originally stated. The "200 year" remark was addressed in URL's page, at http://www.urlpharma.com/url_unapproved_drug_NEJM.aspx. —Preceding unsigned comment added by Andyberks (talk • contribs) 19:13, 26 July 2010 (UTC)[reply]

Peyronie

An anonymous editor made an ungrammatical addition that colchicine is used in Peyronie's disease. Looking through the recent evidence, PMID 18974422 seems to say that colchicine is not presently "state of the art" treatment in Peyronie, and therefore we'd better not mention this fact here. It may be appropriate in passing in the Peyronie article. JFW | T@lk 08:34, 29 March 2009 (UTC)[reply]

Colchicine as treatment for cirrhosis

I have just been diagnosed with cirrhosis due to alcoholism and not due to hepatitis; the diagnosis was last March 12, 2009. My question is, is colchicine considered as a treatment for cirrhosis? My doctor has prescribed this medicine and I am taking it twice a day.

PeterPgl1954 (talk) 07:04, 8 September 2009 (UTC)[reply]