Mitraphylline
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| Names | |
|---|---|
| IUPAC name
Mitraphylline
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| Identifiers | |
| ECHA InfoCard | 100.007.370 |
CompTox Dashboard (EPA)
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| Properties | |
| C21H24N2O4 | |
| Molar mass | 368.1736 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the trees Mitragyna Speciosa, commonly known as Kratom. As a non-narcotic constituent, it also occurs to a signficant amount in the bark of Uncaria tomentosa, Cat’s Claw, along with a number of isomeric alkaloids.[1] Little testing has been done with this compound as an isolate, but its believed to possibly be a selective NMDA-Antagonist, with possible mu- and delta-opioid effects (due to it being an indole and closely related to Mitragynine and 7-Hydroxymitragynine, both of which are mu- and delta-opioid agonists with little to no kappa-opioid receptor affinity).
See also
References
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- ^ H. Stuppner, S. Sturm, and G. Konwalinka, (1992). "HPLC analysis of the main oxindole alkaloids from Uncaria tomentosa". Chromatographia 34 11-12; 597-604.