Evoxine

Evoxine
Clinical data
ATC code	none;
Legal status
Legal status	In general: legal;
Identifiers
	IUPAC name 1-(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol;
CAS Number	522-11-2;
PubChem CID	73416;
CompTox Dashboard (EPA)	DTXSID801028138 ;
Chemical and physical data
Formula	C11H12O2
Molar mass	347.362 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O;

Evoxine (Haploperine) is an alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides^[1] and Teclea gerrardii.^[2]

References

^ Eastwood, FW; Hughes, GK; Ritchie, E. (1954). "Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine". Australian Journal of Chemistry. 7 (1): 87–98. doi:10.1071/CH9540087.
^ Waffo, AF; Coombes, PH; Crouch, NR; Mulholland, DA; El Amin, SM; Smith, PJ (2007). "Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa". Phytochemistry. 68 (5): 663–7. doi:10.1016/j.phytochem.2006.10.011. PMID 17174364.

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