Hispidin
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| Names | |
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| IUPAC name
2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxypyran-4-one
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| Other names
6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
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| Identifiers | |
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3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C13H10O5 | |
| Molar mass | 246.21 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Hispidin is a natural substance. It can also be synthetised.[1]
Hispidin 4-O-β-d-glucopyranoside can be found in Pteris ensiformis[2] whereas hispidin derivatives can be found in the edible mushroom Inonotus xeranticus[3] or Phellinus.[4][5]
References
- ^ Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro. Gonindard C, Bergonzi C, Denier C, Sergheraert C, Klaebe A, Chavant L and Hollande E, Cell Biol Toxicol. 1997 Mar, 13(3), pp. 141-153, PMID 9088624, doi:10.1023/A:1007321227010
- ^ Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.). Yung-Husan Chen, Fang-Rong Chang, Yih-Jer Lin, Lisu Wang, Jinn-Fen Chen, Yang-Chang Wu and Ming-Jiuan Wu, Food Chemistry Volume 105, Issue 1, 2007, pp. 48-56, doi:10.1016/j.foodchem.2007.03.055
- ^ Hispidin Derivatives from the Mushroom Inonotus xeranticus and Their Antioxidant Activity. In-Kyoung Lee, Soon-Ja Seok, Wan-Kyu Kim and Bong-Sik Yun, J. Nat. Prod., 2006, 69 (2), pp. 299–301, doi:10.1021/np050453n
- ^ Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus. In-Kyoung Lee and Bong-Sik Yu, Bioorganic & Medicinal Chemistry, Volume 15, Issue 10, 15 May 2007, pages 3309-3314, doi:10.1016/j.bmc.2007.03.039
- ^ Lee YS, Kang YH, Jung JY; et al. (2008). "Protein glycation inhibitors from the fruiting body of Phellinus linteus" ([dead link]). Biological & Pharmaceutical Bulletin. 31 (10): 1968–72. doi:10.1248/bpb.31.1968. PMID 18827365.
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