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Adams decarboxylation

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The Adams decarboxylation is a chemical reaction that involved the decarboxylation of coumarins which have carboxylic acid group in the third position. The decarboxylation is achieved by aqueous solution of sodium bisulfite, heat and a concentrated solution of sodium hydroxide.[1][2][3]

References

  1. ^ Adams, R.;Mathieu, J. J. Amer. Chem. Soc.1948,70,2120.
  2. ^ Adams, R.;Bockstaheler, T.E. J. Amer. Chem. Soc.1952,74,5346.
  3. ^ Cramer, F.;Windel, H. Chem. Ber. 1956,89,354.