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Sulfadimidine

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Sulfamethazine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-amino-N-(4,6-dimethylpyrimidin-2-yl)
    benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
NIAID ChemDB
CompTox Dashboard (EPA)
ECHA InfoCard100.000.315 Edit this at Wikidata
Chemical and physical data
FormulaC12H14N4O2S
Molar mass278.33 g/mol g·mol−1
3D model (JSmol)
  • O=S(=O)(Nc1nc(cc(n1)C)C)c2ccc(N)cc2
  • InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) checkY
  • Key:ASWVTGNCAZCNNR-UHFFFAOYSA-N checkY
  (verify)

Sulfadimidine or sulfamethazine,[1] is a sulfonamide antibacterial.

There are non-standardizeda abbreviations for it as "sulfadimidine" (abbreviated SDI[2][3] and more commonly but less reliablyb SDD[4][5]) and as "sulfamethazine" (abbreviated SMT[6][7] and more commonly but less reliablyc SMZ[8][9]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[1]

Notes

  • ^a Abbreviations are not found in the databases (such as ChemDB, ChemIDplus, PubChem), but often seen in the published literature.[citation needed]
  • ^b "SDD" is not found in databases, but often seen in the published literature; it could however be confused with Tiferron/Sodium catechol sulfate (1,2-Dihydroxybenzene-3,5-disulfonic acid disodium Salt), uncommon but found officially abbreviated SDD in the ChemIDplus database.[10]
  • ^c "SMZ" is not found in databases, but often seen in the published literature; it could however be confused with sulfamethoxazole, also seen abbreviated SMZ.[citation needed]

References

  1. ^ a b "Sulfadimidine" (in French). Banque de données automatisée sur les médicaments. 15 November 1999. Retrieved 14 September 2009.
  2. ^ Romváry, A; Simon, F (1992). "Sulfonamide residues in eggs". Acta veterinaria Hungarica. 40 (1–2): 99–106. ISSN 0236-6290. PMID 1476095.
  3. ^ Reddy; Jain, S. K.; Uppal, R. P. (1988). "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences.
  4. ^ Kamakura, K; Hasegawa, M; Koiguchi, S; Miyata, M; Okamoto, K; Narita, M; Hirahara, Y; Yamana, T; Tonogai, Y (1993). "Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry". Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. ISSN 0077-4715. PMID 7920569.
  5. ^ Garg, SK; Ghosh, SS; Mathur, VS (1986). "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International journal of clinical pharmacology, therapy, and toxicology. 24 (1): 23–5. ISSN 0174-4879. PMID 3485584. {{cite journal}}: Unknown parameter |month= ignored (help)
  6. ^ Peña, MS; Salinas, F; Mahedero, MC; Aaron, JJ (1994). "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta. 41 (2): 233–6. doi:10.1016/0039-9140(94)80113-4. ISSN 0039-9140. PMID 18965913. {{cite journal}}: Unknown parameter |month= ignored (help)
  7. ^ Kaniou, S; Pitarakis, K; Barlagianni, I; Poulios, I (2005). "Photocatalytic oxidation of sulfamethazine". Chemosphere. 60 (3): 372–80. doi:10.1016/j.chemosphere.2004.11.069. ISSN 0045-6535. PMID 15924956. {{cite journal}}: Unknown parameter |month= ignored (help)
  8. ^ Calvo, R; Sarabia, S; Carlos, R; Du Souich, P (1987). "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & drug disposition. 8 (2): 115–24. doi:10.1002/bdd.2510080203. ISSN 0142-2782. PMID 3593892. {{cite journal}}: Unknown parameter |month= ignored (help)
  9. ^ De Liguoro, M; Fioretto, B; Poltronieri, C; Gallina, G (2009). "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere. 75 (11): 1519–24. doi:10.1016/j.chemosphere.2009.02.002. ISSN 0045-6535. PMID 19269673. {{cite journal}}: Unknown parameter |month= ignored (help)
  10. ^ http://chem.sis.nlm.nih.gov/chemidplus/ProxyServlet?objectHandle=Search&actionHandle=getAll3DMViewFiles&nextPage=jsp%2Fcommon%2FChemFull.jsp%3FcalledFrom%3Dlite&chemid=000149451&formatType=_3D[dead link]

Further reading