Chloroxylenol
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| Names | |
|---|---|
| Systematic IUPAC name
4-Chloro-3,5-dimethylphenol[1] | |
| Identifiers | |
3D model (JSmol)
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| 1862539 | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.001.631 |
| EC Number |
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| KEGG | |
| MeSH | chloroxylenol |
PubChem CID
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C8H9ClO | |
| Molar mass | 156.61 g·mol−1 |
| log P | 3.377 |
| Acidity (pKa) | 9.76 |
| Basicity (pKb) | 4.24 |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H302, H315, H317, H319 | |
| P280, P305+P351+P338 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chloroxylenol (4-chloro-3,5-dimethylphenol) is an antimicrobial chemical compound used to control bacteria, algae, and fungi in adhesives, emulsions, paints, and wash tanks.[2] It is also commonly used in antibacterial soaps such as Dettol and ointments, such as the now discontinued Medicated Vaseline.[3] Studies have shown a low anti microbial activity which is enhanced by additives. Its antibacterial action is due to disruption of cell membrane potentials.[4]
Chloroxylenol is not significantly toxic to humans and other mammals, is practically non-toxic to birds, moderately toxic to freshwater invertebrates and highly toxic to fish.[2] It is a mild skin irritant and may trigger allergic reactions in some individuals. Cross sensitivity with chlorocresol is common.[3]
References
- ^ "chloroxylenol - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification and Related Records. Retrieved 7 October 2011.
- ^ a b http://www.epa.gov/oppsrrd1/REDs/factsheets/3045fact.pdf
- ^ a b Ascenzi, Joseph M. (1996). "Chloroxylenol: an old-new antimicrobial". Handbook of disinfectants and antiseptics. New York: M. Dekker. ISBN 978-0-8247-9524-5.
- ^ Aly, R; Malbach, H (1988). "Comparative antibacterial efficacy of a 2-minute surgical scrub with chlorhexidine gluconate, povidone-iodine, and chloroxylenol sponge-brushes". American Journal of Infection Control. 16 (4): 173–7. doi:10.1016/0196-6553(88)90029-6. PMID 3189943.
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