Longitudinal callosal fascicle
Longitudinal callosal fascicles (or Probst bundles) are abnormal collections of brain cells characteristic of patients with Agenesis of the corpus callosum. Failure of the neurons that normally make up the corpus callosum to cross the midline[clarification needed] results in anomalous collection of these cells in both hemispheres. Longitudinal callosal fascicles were originally described by Moriz Probst in 1901 by gross anatomical observation.[1] More recently, these anomalies are detected by Magnetic Resonance Imaging [2] or Diffusion Tensor Imaging.[3]
References
- ^ Probst, M. (1901), "Über den Bau des vollständing balkenlosen Großhirns", Arch Psychiatr, 34: 709–786
- ^ Barkovich, AJ.; Norman, D. (1988), "Anomalies of the corpus callosum: correlation with further anomalies of the brain.", AJR Am J Roentgenol, 151 (1): 171–9, PMID 3259802
{{citation}}: Unknown parameter|month=ignored (help) - ^ Lee, SK.; Mori, S.; Kim, DJ.; Kim, SY.; Kim, SY.; Kim, DI. (2004). "Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis". AJNR Am J Neuroradiol. 25 (1): 25–8. PMID 14729523.
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