2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
| 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.11.34 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (EC 1.14.11.34, ethylene-forming enzyme, EFE) is an enzyme with system name L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- 2-oxoglutarate + L-arginine + O2 succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O (overall reaction)
- (1a) 2-oxoglutarate + L-arginine + O2 succinate + CO2 + L-hydroxyarginine
- (1b) L-hydroxyarginine guanidine + (S)-1-pyrroline-5-carboxylate + H2O
2-oxoglutarate/L-arginine monooxygenase/decarboxylase catalyses two cycles of the ethylene-forming reaction.
References
- ^ Nagahama, K., Ogawa, T., Fujii, T., Tazaki, M., Tanase, S., Morino, Y. and Fukuda, H. (1991). "Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2". J. Gen. Microbiol. 137: 2281–2286. PMID 1770346.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Fukuda, H., Ogawa, T., Tazaki, M., Nagahama, K., Fujii, T., Tanase, S. and Morino, Y. (1992). "Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae". Biochem. Biophys. Res. Commun. 188: 483–489. PMID 1445291.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Fukuda, H., Ogawa, T., Ishihara, K., Fujii, T., Nagahama, K., Omata, T., Inoue, Y., Tanase, S. and Morino, Y. (1992). "Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2". Biochem. Biophys. Res. Commun. 188: 826–832. PMID 1445325.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- 2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)