3-hydroxyindolin-2-one monooxygenase
| 3-hydroxyindolin-2-one monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.139 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
3-hydroxyindolin-2-one monooxygenase (EC 1.14.13.139, BX4 (gene), CYP71C1 (gene)) is an enzyme with system name 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O
3-hydroxyindolin-2-one monooxygenase is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants.
References
- ^ Glawischnig, E., Grun, S., Frey, M. and Gierl, A. (1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry. 50: 925–930. PMID 10385992.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Frey, M., Chomet, P., Glawischnig, E., Stettner, C., Grün, S., Winklmair, A., Eisenreich, W., Bacher, A., Meeley, R.B., Briggs, S.P., Simcox, K. and Gierl, A. (1997). "Analysis of a chemical plant defense mechanism in grasses". Science. 277: 696–699. PMID 9235894.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Spiteller, P., Glawischnig, E., Gierl, A. and Steglich, W. (2001). "Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays". Phytochemistry. 57: 373–376. PMID 11393516.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- 3-hydroxyindolin-2-one+monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)