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Norleucine

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Norleucine
Names
IUPAC name
2-aminohexanoic acid
Other names
Caprine
Glycoleucine
Identifiers
3D model (JSmol)
1721748
ChEBI
ChemSpider
DrugBank
ECHA InfoCard 100.009.512 Edit this at Wikidata
EC Number
  • 210-462-7
464584
KEGG
MeSH Norleucine
RTECS number
  • RC6308000
UNII
  • InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
    Key: LRQKBLKVPFOOQJ-UHFFFAOYSA-N
  • CCCCC(N)C(O)=O
Properties
C6H13NO2
Molar mass 131.175 g·mol−1
Melting point 301 °C (decomposes) [1]
16 g/l at 23 °C [2]
Acidity (pKa) 2.39 (carboxyl), 9.76 (amino)[3]
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Norleucine (abbreviated as Nle) is an isomer of leucine, the α-amino acid 2-amino-hexanoic acid. It is not found in natural proteins. Norleucine is used in experimental studies of protein structure and function.

See also

  • Leucines, description of the isomers of leucine

References

  1. ^ Hermann Römpp, Jürgen Falbe und Manfred Regitz: Römpp Lexikon Chemie, 9. Auflage, Georg Thieme Verlag, Stuttgart 1992.
  2. ^ Sicherheitsdatenblatt Acros.
  3. ^ Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959.