Norleucine
Appearance
Names | |
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IUPAC name
2-aminohexanoic acid
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Other names
Caprine
Glycoleucine | |
Identifiers | |
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3D model (JSmol)
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1721748 | |
ChEBI | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.009.512 |
EC Number |
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464584 | |
KEGG | |
MeSH | Norleucine |
PubChem CID
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RTECS number |
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C6H13NO2 | |
Molar mass | 131.175 g·mol−1 |
Melting point | 301 °C (decomposes) [1] |
16 g/l at 23 °C [2] | |
Acidity (pKa) | 2.39 (carboxyl), 9.76 (amino)[3] |
Related compounds | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Norleucine (abbreviated as Nle) is an isomer of leucine, the α-amino acid 2-amino-hexanoic acid. It is not found in natural proteins. Norleucine is used in experimental studies of protein structure and function.
See also
- Leucines, description of the isomers of leucine
References
- ^ Hermann Römpp, Jürgen Falbe und Manfred Regitz: Römpp Lexikon Chemie, 9. Auflage, Georg Thieme Verlag, Stuttgart 1992.
- ^ Sicherheitsdatenblatt Acros.
- ^ Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959.