Sign of Hertoghe
The Sign of Hertoghe or Queen Anne's sign is a thinning or loss of the outer third of the eyebrows, and is a sign of hypothyroidism or dermatitis atopica. The sign is named after Eugene Hertoghe of Antwerp, a pioneer in thyroid function research.[1][2]
Queen Anne's sign
The association with Anne of Denmark is based on portraiture, although history does not suggest that she suffered an underactive thyroid.[3] The eponym is disputed by some, though it has been suggested that Anne of France, Anne of Brittany, Anne of Austria, Anne Boleyn and Anne of Cleves may all be eliminated as candidates.[4]
References
- ^ Schatz, Henry A. (1922-05). "The Role of the Thyroid Gland in Otolaryngology". The Pennsylvania Medical Journal. 25 (8): 529.
{{cite journal}}:|access-date=requires|url=(help); Check date values in:|date=(help); Cite has empty unknown parameter:|coauthors=(help) - ^ "Complimentary Dinner given by Dr. William Seaman Bainbridge". American Medicine. 9 (4): 308. 1914-04.
{{cite journal}}:|access-date=requires|url=(help);|first=has generic name (help);|first=missing|last=(help); Check date values in:|date=(help); Cite has empty unknown parameter:|coauthors=(help) - ^ Lane Furdell E (2007). "Eponymous, anonymous: Queen Anne's sign and the misnaming of a symptom". J Med Biogr. 15 (2): 97–101. PMID 17551609.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Keynes M (2009). "Letter to the editor". J Med Biogr. 17 (1): 62. doi:10.1258/jmb.2007.007021. PMID 19190203.
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