Nicotinate dehydrogenase (cytochrome)
| Nicotinate dehydrogenase (cytochrome) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.17.2.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Nicotinate dehydrogenase (cytochrome) (EC 1.17.2.1, nicotinic acid hydroxylase, nicotinate hydroxylase) is an enzyme with system name nicotinate:cytochrome 6-oxidoreductase (hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
- nicotinate + a ferricytochrome + H2O 6-hydroxynicotinate + a ferrocytochrome + 2 H+
This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases.
References
- ^ Jimenez, J.I., Canales, A., Jimenez-Barbero, J., Ginalski, K., Rychlewski, L., Garcia, J.L. and Diaz, E. (2008). "Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440". Proc. Natl. Acad. Sci. USA. 105: 11329–11334. PMID 18678916.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Yang, Y., Yuan, S., Chen, T., Ma, P., Shang, G. and Dai, Y. (2009). "Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440". Biodegradation. 20: 541–549. PMID 19118407.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
See also
External links
- Nicotinate+dehydrogenase+(cytochrome) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)