User:LaurenSMS4/sandbox

This is the user sandbox of LaurenSMS4. A user sandbox is a subpage of the user's user page. It serves as a testing spot and page development space for the user and is not an encyclopedia article. Create or edit your own sandbox here.

Other sandboxes: Main sandbox | Template sandbox

Finished writing a draft article? Are you ready to request review of it by an experienced editor for possible inclusion in Wikipedia? Submit your draft for review!

Proliferative disorders

An increase in the number of white blood cells in circulation is called leukocytosis.^[1] This increase is most commonly caused by inflammation.^[1] There are four major causes: increase of production in bone marrow, increased release from storage in bone marrow, decreased attachment to veins and arteries, decreased uptake by tissues.^[1] Leukocytosis may affect one or more cell lines and can be neutrophilic, eosinophilic, basophilic, monocytosis, or lymphocytosis.

Neutrophilia

Neutrophilia is an increase in the absolute neutrophil count in the peripheral circulation. Normal blood values vary by age.^[2] Neutrophilia can be caused by a direct problem with blood cells (primary disease). It can also occur as a consequence of an underlying disease (secondary). Most cases of neutrophilia are secondary to inflammation.^[3]

Primary Causes^[4]

Conditions with normally functioning neutrophils - hereditary neutrophilia, chronic idiopathic neutrophilia
Pelger-Huet Anomaly
Down syndrome
Leukocyte adhesion deficiency
Familial cold urticaria
Leukemia (chronic myelogenous (CML)) and other myeloproliferative disorders
Surgical removal of spleen

Secondary Causes^[5]

Infection
Chronic inflammation - especially juvenile rheumatoid arthritis, rheumatoid arthritis, Still's disease, Crohn's disease, ulcerative colitis, granulomatous infections (for example, tuberculosis), and chronic hepatitis
Cigarette smoking - occurs in 25-50% of chronic smokers and can last up to 5 years after quitting
Stress - exercise, surgery, general stress
Medication induced - corticosteroids (for example, prednisone, β-agonists, lithium
Cancer - either by growth factors secreted by the tumor or invasion of bone marrow by the cancer
Increased destruction of cells in peripheral circulation can stimulate bone marrow. This can occur in hemolytic anemia and idiopathic thrombocytopenic purpura

Eosinophilia

^ ^a ^b ^c Cite error: The named reference Al2010 was invoked but never defined (see the help page).
^ Cite error: The named reference Al2010a was invoked but never defined (see the help page).
^ Cite error: The named reference Schafer was invoked but never defined (see the help page).
^ Schafer, [edited by] Lee Goldman, Andrew I. Goldman's Cecil medicine (24th ed. ed.). Philadelphia: Elsevier/Saunders. ISBN 1437716040. {{cite book}}: |edition= has extra text (help); |first= has generic name (help)CS1 maint: multiple names: authors list (link)
^ Schafer, [edited by] Lee Goldman, Andrew I. Goldman's Cecil medicine (24th ed. ed.). Philadelphia: Elsevier/Saunders. ISBN 1437716040. {{cite book}}: |edition= has extra text (help); |first= has generic name (help)CS1 maint: multiple names: authors list (link)

[Al2010-1] Cite error: The named reference Al2010 was invoked but never defined (see the help page).

[Al2010a-2] Cite error: The named reference Al2010a was invoked but never defined (see the help page).

[Schafer-3] Cite error: The named reference Schafer was invoked but never defined (see the help page).

[4] Schafer, [edited by] Lee Goldman, Andrew I. Goldman's Cecil medicine (24th ed. ed.). Philadelphia: Elsevier/Saunders. ISBN 1437716040. {{cite book}}: |edition= has extra text (help); |first= has generic name (help)CS1 maint: multiple names: authors list (link)

[5] Schafer, [edited by] Lee Goldman, Andrew I. Goldman's Cecil medicine (24th ed. ed.). Philadelphia: Elsevier/Saunders. ISBN 1437716040. {{cite book}}: |edition= has extra text (help); |first= has generic name (help)CS1 maint: multiple names: authors list (link)

[1]

[2]

[3]

[4]

[5]