Hispidin

Hispidin
Names
	IUPAC name 2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxypyran-4-one
	Other names 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
Identifiers
CAS Number	555-55-5 =;
3D model (JSmol)	Interactive image;
ChemSpider	13975015 ;
PubChem CID	5353671;
CompTox Dashboard (EPA)	DTXSID401017256 ;
	InChI InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+ Key: SGJNQVTUYXCBKH-HNQUOIGGSA-N ; InChI=1/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+ Key: SGJNQVTUYXCBKH-HNQUOIGGBX;
	SMILES OC=2/C=C(/C=C/c1ccc(O)c(O)c1)OC(=O)C=2;
Properties
Molar mass	246.21 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Hispidin is a natural substance. It can also be synthetised.^[1]

Hispidin 4-O-β-d-glucopyranoside can be found in Pteris ensiformis^[2] whereas hispidin derivatives can be found in the edible mushroom Inonotus xeranticus^[3] or Phellinus.^[4]^[5]

References

^ Gonindard, C.; Bergonzi, C.; Denier, C.; Sergheraert, C.; Klaebe, A.; Chavant, L.; Hollande, E. (1997). "Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro". Cell Biology and Toxicology. 13 (3): 141–53. doi:10.1023/A:1007321227010. PMID 9088624.
^ Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.). Yung-Husan Chen, Fang-Rong Chang, Yih-Jer Lin, Lisu Wang, Jinn-Fen Chen, Yang-Chang Wu and Ming-Jiuan Wu, Food Chemistry Volume 105, Issue 1, 2007, pp. 48-56, doi:10.1016/j.foodchem.2007.03.055
^ Hispidin Derivatives from the Mushroom Inonotus xeranticus and Their Antioxidant Activity. In-Kyoung Lee, Soon-Ja Seok, Wan-Kyu Kim and Bong-Sik Yun, J. Nat. Prod., 2006, 69 (2), pp. 299–301, doi:10.1021/np050453n
^ Lee, In-Kyoung; Yun, Bong-Sik (2007). "Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus". Bioorganic & Medicinal Chemistry. 15 (10): 3309. doi:10.1016/j.bmc.2007.03.039.
^ Lee, Yeon Sil; Kang, Young-Hee; Jung, Ju-Young; Lee, Sanghyun; Ohuchi, Kazuo; Shin, Kuk Hyun; Kang, Il-Jun; Park, Jung Han Yoon; et al. (October 2008). "Protein glycation inhibitors from the fruiting body of Phellinus linteus" (^{[dead link‍]}). Biological & Pharmaceutical Bulletin. 31 (10): 1968–72. doi:10.1248/bpb.31.1968. PMID 18827365.