GNA12
Appearance
Template:PBB Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.[1][2][3]
Interactions
GNA12 has been shown to interact with ARHGEF1,[4] PPP5C,[5] ARHGEF12,[6][7] Heat shock protein 90kDa alpha (cytosolic), member A1[8] and TEC.[7]
See also
References
- ^ Chan AM, Fleming TP, McGovern ES, Chedid M, Miki T, Aaronson SA (February 1993). "Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product". Mol Cell Biol. 13 (2): 762–8. PMC 358958. PMID 8423800.
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: CS1 maint: multiple names: authors list (link) - ^ Kumar RN, Shore SK, Dhanasekaran N (February 2006). "Neoplastic transformation by the gep oncogene, Galpha12, involves signaling by STAT3". Oncogene. 25 (6): 899–906. doi:10.1038/sj.onc.1209132. PMID 16247467.
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: CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: GNA12 guanine nucleotide binding protein (G protein) alpha 12".
- ^ Johnson EN, Seasholtz TM, Waheed AA; et al. (December 2003). "RGS16 inhibits signalling through the G alpha 13-Rho axis". Nat. Cell Biol. 5 (12): 1095–103. doi:10.1038/ncb1065. PMID 14634662.
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(help)CS1 maint: multiple names: authors list (link) - ^ Yamaguchi, Yoshiaki (August 2002). "Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity". Curr. Biol. 12 (15). England: 1353–8. doi:10.1016/S0960-9822(02)01034-5. ISSN 0960-9822. PMID 12176367.
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suggested) (help) - ^ Fukuhara, S; Chikumi H; Gutkind J S (November 2000). "Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho". FEBS Lett. 485 (2–3). NETHERLANDS: 183–8. doi:10.1016/S0014-5793(00)02224-9. ISSN 0014-5793. PMID 11094164.
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(help) - ^ a b Suzuki, Nobuchika (January 2003). "Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF". Proc. Natl. Acad. Sci. U.S.A. 100 (2). United States: 733–8. doi:10.1073/pnas.0234057100. ISSN 0027-8424. PMC 141065. PMID 12515866.
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suggested) (help) - ^ Vaiskunaite, R; Kozasa T; Voyno-Yasenetskaya T A (December 2001). "Interaction between the G alpha subunit of heterotrimeric G(12) protein and Hsp90 is required for G alpha(12) signaling". J. Biol. Chem. 276 (49). United States: 46088–93. doi:10.1074/jbc.M108711200. ISSN 0021-9258. PMID 11598136.
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External links
- GNA12+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)