Secosteroid
Secosteroids (sec·o·ster·oid, sek'ō-stēr'oyd) are a subclass of the tetracyclic steroid class that are structural relatives bearing a cleavage of one of the four rings of that parent class.[1] The subclass nomenclature derives from the verb Template:Lang-lat meaning "to cut", and Template:Lang-lat of steroid, meaning "solid, three-dimensional".[2] Subclasses are defined by the carbon atoms of the parent steroid skeleton where the ring cleavage has taken place, e.g., 9,10-secosteroids for derivatives deriving from cleavage between carbon atoms C9 and C10 of the steroid B-ring (similarly 5,6-secosteroids, 13,14-steroids, etc.).
The prototypical secosteroid is cholecalciferol, vitamin D3.[3]
References
- ^ See for instance, the drugs.com [1], free (medical) dictionary [2], biology-online [3], and medilexicon [4] entries for this term.
- ^ Donald Ayers, 1972, Bioscientific Terminology, Tucson: University of Arizona Press, pp. 241, 129. ISBN 978-0-8165-0305-6. See http://www.uapress.arizona.edu/Books/bid18.htm, accessed 10 May 2014.
- ^ See, for instance, J.R. Hanson, 2010, "Steroids: partial synthesis in medicinal chemistry, Nat Prod Rep. 27(6):887-99. doi: 10.1039/c001262a, PMID: 20424788. See http://pubs.rsc.org/en/content/articlelanding/2010/np/c001262a#!divAbstract, accessed 10 May 2014.
External links
- Secosteroids at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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