Ziegler process

In organic chemistry, the Ziegler process is an method for producing fatty alcohols from ethylene using organoaluminium catalyst.The Ziegler Alcohol Process, or commonly called the Ziegler-Alfol synthesis, is a technology for the production of linear primary alcohols with an even number carbon chain. The process uses an aluminum catalyst to oligomerize ethylene and allow the resulting alkyl group to be oxygenated. The usually targeted products are fatty alcohols, which are otherwise derived from natural fats and oils. Fatty alcohols are used in food and chemical processing. They are useful due to their amphipathic nature. The synthesis route is named after Karl Zeigler, who described the process in 1955.
=== Mechanism ===
The Ziegler alcohol synthesis involves oligomerization of ethylene using triethylaluminium followed by oxidation.² The triethylaluminium, the Ziegler catalyst, is synthesized by action of aluminum, ethylene, and hydrogen gas. In the production process, two-thirds of the triethylaluminium produced is recycled back into the reactor, and only one-third is used to produce the fatty alcohols.² The recycling step is used to produce triethylaluminium at a higher yield and with less time, making the overall process more efficient. Triethylaluminium reacts with ethylene to form higher molecular weight trialkylaluminium. The number of equivalents of ethylene n equals the total number of monomer units being grown on the initial ethylene chains, where (n = x + y + z), and x, y, and z are the number of ethylene units per chain. Trialkylaluminium is oxidized with air to form aluminum alkoxides, and finally hydrolyzed to aluminum hydroxide and the desired alcohols.²
1. Al+3ethylene+1.4H₂ → Al(C₂H₅)₃
2. Al(C₂H₅)₃ n-ethylene → Al((CH₂CH₂)_nCH₂CH₃)₃
3. Al((CH₂CH₂)_nCH₂CH₃)₃+ O₂ → Al(O(CH₂CH₂)_nCH₂CH₃)₃
4. Al(O(CH₂CH₂)_nCH₂CH₃)₃ → Al(OH)₃ + CH₃CH₂(CH₂C₂)_mOH

The temperature of the reaction influences the molecular weight of alcohol growth. Temperatures in the range of 60-120⁰C form higher molecular weight trialkylaluminium while higher temperatures (e.g., 120-150⁰C) cause thermal displacement reactions that afford α-olefin chains. Above 150⁰C, dimerization of the α-olefins occurs.

Applications

Aluminum hydroxide, the byproduct of the synthesis, can be dehydrated to give alumina, which at high purities has a high commercial value. One modification of the Ziegler process is called the EPAL process.² In this process, chain growth is optimized to produce alcohols with narrow molecular weight distribution. Synthesis of other alcohols use Ziegler and the updated EPAL process, such as the transalkylation of styrene to form 2-phenylethanol. Alternate catalysts include diethylaluminum hydride, and further use of trialkylaluminium for oxyethylations have been implemented.¹