Jump to content

Allergy to cats

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Stamptrader (talk | contribs) at 10:44, 15 February 2015 (corrected CS1 error). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Cat allergy in humans is an allergic reaction to one or more allergens produced by cats. The most common of these allergens are the glycoprotein Fel d 1, secreted by the cat's sebaceous glands and Fel d 4, which is expressed in saliva. An allergic reaction is a histamine reaction that is usually characterized by coughing, wheezing, chest tightening, itching, nasal congestion, rash, watering eyes, sneezing, chapped lips, and similar symptoms.

Cat allergens

Five cat allergens have been described in medical literature. The two major allergens are Fel d 1 (a secretoglobin) and Fel d 4 (a lipocalin). The minor allergens include Fel d 2 (an albumin), Fel d 3 (a cystatin), and cat IgA.[1]

Fel d 4 is the product of the cat major urinary protein gene. It is primarily expressed in the submandibular salivary gland and is deposited onto dander as the cat grooms itself. A study found that 63% of cat allergic people have antibodies against Fel d 4.[2]

Symptoms

Symptoms of an allergic reaction to cats include swollen, red, itchy, and watery eyes; nasal congestion, itchy nose, sneezing, chronic sore throat or itchy throat, coughing, wheezing, asthma, hay fever,[3] hives or rash on the face or chest, or itchy skin. If a cat has scratched, licked, or bitten someone who is allergic to cats, redness will occur.[4] Symptoms are often confused with a common cold.[5]

Coping with allergies

Lower exposure

Allergens are airborne and survive for months or even years by themselves, hence removing anything that can trap and hold the allergens (carpet, rugs, pillows) and cleaning regularly and thoroughly with HEPA filters and electrostatic air purifier systems reduces risk. Frequent hand washing, especially after handling the cat, and washing hands prior to touching eyes, nose, or mouth, and limiting the cat's access to certain rooms, such as the bedroom or other rooms where much time is spent, may also reduce allergic reactions.

Medications

Cat allergies can often be controlled with over the counter or prescription medications. Antihistamines and decongestants may provide allergy relief.[6]

Allergy shots

Some allergy sufferers find relief in allergen immunotherapy, a periodic injection therapy designed to stimulate the body's natural immune responses to the cat allergens.[7][8]

Synthetic epitope vaccine

The Synthetic epitope vaccine is an in-development vaccine to provide a long term vaccine for allergies.[9]

Cat bathing

Regularly bathing the cat may remove significant amounts of allergens from the fur.[10] Furthermore, regularly brushing the cat will reduce the amount of loose fur (and its attached saliva) in the air. Feeding the cat a high quality diet with plenty of omega-3 fatty acids will help keep the coat healthy and minimize dander.[11]

Hypoallergenic cats

A hypoallergenic cat is a cat that is less likely to provoke an allergic reaction in humans. Although the topic is controversial, with many studies showing statistically significant results,[12] owners' experience and recent clinical studies suggest that Siberian cats, Devon Rex and Cornish Rex cats, Abyssinian cats, Balinese cats, Oriental Shorthair, and several other breeds, especially females, are likely to have low levels of Fel d 1, the main allergenic protein.[13][dead link‍]

In 2006, the Allerca company announced the successful breeding of a line of hypoallergenic cats. However, no peer-reviewed studies have been done to confirm their claims and many scientists and consumers are skeptical of the company's assertions.[14] The company has announced that on January 1, 2010 they will cease their breeding activities.[15]

Another company, Felix Pets, also claims to be developing a breed of hypoallergenic cat.[16]

Cat gender and color

Female cats produce a lower level of allergens than males, and neutered males produce a lower level of allergens than unaltered males.[17] In 2000, researchers at the Long Island College Hospital found that cat owners with dark-colored cats were more likely to report allergy symptoms than those with light-colored cats.[18][19][20] A later study by the Wellington Asthma Research Group found that fur color had no effect on how much allergen a cat produced.[21][22]

See also

References

  1. ^ Adédoyin J, et al. "Cat IgA, representative of new carbohydrate cross-reactive allergens" The Journal of Allergy and Clinical Immunology, 2007-3. Retrieved on 2009-8-1.
  2. ^ Smith W; Butler AJ; Hazell LA; Chapman MD; Pomés A; Nickels DG; et al. (2004). "Fel d 4, a cat lipocalin allergen". Clin Exp Allergy. 34 (11): 1732–8. doi:10.1111/j.1365-2222.2004.02090.x. PMID 15544598. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  3. ^ "Allergy to pets and animals". allergyclinic.co.uk. Retrieved 9 November 2011.
  4. ^ "WebMD - Cat Allergies". WebMD, LLC. Retrieved 9 November 2011.
  5. ^ "Human Allergies to Cats". Foster & Smith, Inc. Retrieved 9 November 2011.
  6. ^ Cat Allergies, WebMD, http://www.webmd.com/allergies/cat-allergies
  7. ^ Clinical efficacy of specific immunotherapy to cat dander: a double-blind placebo-controlled trial http://www.jacionline.org/medline/record/ivp_09547894_27_860. Accessed 08 Jan 2011.
  8. ^ Immunotherapy with cat- and dog-dander extracts. V. Effects of 3 years of treatment. http://www.jacionline.org/medline/record/ivp_00916749_87_955. Accessed 08 Jan 2011.
  9. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 16998509, please use {{cite journal}} with |pmid=16998509 instead.
  10. ^ Evaluation of different techniques for washing cats: Quantitation of allergen removed from the cat and the effect on airborne Fel d 1 http://www.jacionline.org/article/S0091-6749(97)70242-2/fulltext. Retrieved 10 Jan 2011.
  11. ^ Human Allergies to Cats. http://www.peteducation.com/article.cfm?c=0+1278&aid=144
  12. ^ Hypoallergenic Cats - Do They Exist? http://www.cat-world.com.au/hypoallergenic-cats-do-they-exist Accessed 10 Jan 2011.
  13. ^ http://www.siberianresearch.com/index.php?option=com_content&view=article&id=125:siberian-allergen-levels&catid=45:allergens&Itemid=75
  14. ^ Felis Enigmaticus
  15. ^ "Lifestyle Pets". Allerca. Archived from the original on 2009-11-01. Retrieved 2009-11-01.
  16. ^ Pepling, Racheal. (9 June 2006)."Hypoallergenic" Cats For Sale, U.S. Firm Announces. National Geographic News. Accessed 13 March 2010.
  17. ^ Sex difference in Fel d 1 allergen production. http://www.jacionline.org/article/S0091-6749(96)70238-5/fulltext . Accessed 11 Jan 2011.
  18. ^ preliminary results, cited in Prevention (magazine)
  19. ^ full study, cited in the Journal of the American Medical Association
  20. ^ Hussain S, Bassett C, Kaplan S, Schneider A, Silverman B. (2000). "Correlation between the color of cat hair and severity of allergic symptoms in patients with allergic rhinitis". Journal of Allergy and Clinical Immunology. 105(1 Part 2):S5.
  21. ^ cited by Allergy New Zealand
  22. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi: 10.1067/mai.2001.118788, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi= 10.1067/mai.2001.118788 instead.
Retrieved from "https://en.wikipedia.org/enwiki/w/index.php?title=Allergy_to_cats&oldid=647228855"