Film coating
Appearance
This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages)
|
A film coating is a thin polymer-based coat applied to a solid dosage form such as a tablet. The thickness of such a coating is usually between 20-100 µm.[1] It is possible to follow the dynamic curing effect on tablet coating structure by using non-destructive analytical methodologies.[2]
Film coating formulations usually contain the following components:
- Polymer
- Plasticizer
- Colourant
- Opacifier
- Solvent
- Vehicle
Functionality wise it is further divided into:
- Immediate release coating
- Sustained release or modified release coating
- Enteric release coating
References
- ^ Felton, Linda A; Porter, Stuart C (2013). "An update on pharmaceutical film coating for drug delivery". Expert Opinion on Drug Delivery. 10 (4): 421–35. doi:10.1517/17425247.2013.763792. PMID 23339342.
- ^ Gendre C., Genty M., César da Silva J., Tfayli A., Boiret M., Lecoq O., Baron M., Chaminade P., Péan J-M., Comprehensive study of dynamic curing effect on tablet coating structure, Eur. J. Pharm. Biopharm., 81 (2012), 657-665