TDM

Big Saddo down syndrome boy who is knowen for drinking piss

• DanTDM, or The Diamond Minecart, a YouTube channel operated by Daniel Middleton, a British YouTube personality
• Target Disk Mode, a boot mode on certain Macs
• TDM (Macau) or Teledifusão de Macau (Portuguese for "Television of Macau"), one of the major television stations in Macau, China
• Telecomunicações de Moçambique (Portuguese for "Mozambique Telecoms"), a telecom operator
• Teresian Daughters of Mary, a diocesan religious institute of women in Davao City under the protection of the archbishop of the Roman Catholic Archdiocese of Davao
• Text and Data Mining, a process of deriving high-quality information from text (sometimes in the context of copyright exemptions)
• The Difference Machine, an album by Big Big Train
• Therapeutic drug monitoring, a branch of clinical chemistry
• Time-division multiplexing, a method of transmitting and receiving independent signals over a common signal path
• Toad Data Modeler, database design tool
• Transportation demand management, also traffic demand management or travel demand management
• Yamaha TDM, a motorcycle