NCAPG2

NCAPG2
Identifiers
Aliases	NCAPG2, CAP-G2, CAPG2, LUZP5, MTB, hCAP-G2, non-SMC condensin II complex subunit G2, 3KS
External IDs	OMIM: 608532; MGI: 1923294; HomoloGene: 9820; GeneCards: NCAPG2; OMA:NCAPG2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	158,704,804 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	116,427,351 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; secondary oocyte; ; sperm; ; ganglionic eminence; ; bone marrow; ; bone marrow cells; ; trabecular bone; ; stromal cell of endometrium; ; gonad; ; right testis;
	Top expressed in
	nasal epithelium; ; olfactory epithelium; ; secondary oocyte; ; primary oocyte; ; zygote; ; ventricular zone; ; fetal liver hematopoietic progenitor cell; ; tail of embryo; ; dermis; ; superior cervical ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methylated histone binding; protein binding; bHLH transcription factor binding; molecular function regulator;
Cellular component	membrane; nucleus; nucleoplasm; condensin complex; nuclear speck;
Biological process	cell division; cell cycle; chromosome condensation; inner cell mass cell proliferation; transcription by RNA polymerase II; erythrocyte differentiation; negative regulation of erythrocyte differentiation; positive regulation of protein tyrosine kinase activity; positive regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	54892
	76044
	ENSG00000146918
	ENSMUSG00000042029
	Q86XI2
	Q6DFV1
	NM_001281932; NM_001281933; NM_017760
	NM_133762
	NP_001268861; NP_001268862; NP_060230
	NP_598523
	Wikidata
View/Edit Human	View/Edit Mouse

Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene.^[5]^[6] CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146918 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042029 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (Oct 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ "Entrez Gene: NCAPG2 non-SMC condensin II complex, subunit G2".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Smith ED, Xu Y, Tomson BN, et al. (2004). "More than blood, a Novel Gene Required for Mammalian Postimplantation Development". Mol. Cell. Biol. 24 (3): 1168–73. doi:10.1128/MCB.24.3.1168-1173.2004. PMC 321451. PMID 14729962.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000146918 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042029 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14532007-5] Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (Oct 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[entrez-6] "Entrez Gene: NCAPG2 non-SMC condensin II complex, subunit G2".

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References

Further reading