Lisa Goodrich
Lisa V. Goodrich is a Professor of Neurobiology at the Harvard Medical School.
Lisa Goodrich | |
|---|---|
| Born | |
| Nationality | American |
| Alma mater | Harvard University Stanford University |
| Scientific career | |
| Fields | Neurobiology |
| Institutions | Harvard University |
| Doctoral advisor | Matthew Scott |
| Website | goodrich |
Biography
She grew up in Concord, Massachusetts and she received her degree in Biology from Harvard University in 1991. After graduating from Harvard, she completed her Ph.D program in Neuroscience at Stanford University in 1998. Following the completion of this Ph.D program, she did a postdoctoral fellowship under Marc Tessier-Lavigne at the University of California. While concluding her postdoctoral fellowship, she cultivated a particular interest in the auditory system and utilized her familiarity with molecular genetics and cell behavior, and applied it to the sensory system. Lisa currently resides in Newton, Massachusetts. She enjoys reading and cooking.[1]
Research
In her laboratory, her group studies the cellular and molecular mechanisms that impact the development of neural circuits. The stages of development being studied are determination, differentiation, how axonal connections are formed, and generation of behavior. Her research program focuses on detecting genes necessary for hearing and balance. Her research hopes to connect molecular pathways that are essential in cochlea development, and to influence these pathways to repair the cochlea after suffering damage.[2] It focuses on how the steps of circuit assembly coincide to construct neural networks that are committed to particular functions. In order to do so, research from mouse molecular genetics and genomics is studied to discover how circuit assembly is regulated. The two main assemblies she studies are the auditory circuit assembly and the rental circuit assembly.[3] Her lab utilizes various genetic techniques in mice and biochemical assays and embryological studies in chicks. She also uses forward and reverse genetic approaches in mice to gain an understanding of how genetic mutations can lead to fluctuations in hearing and balances..[4]
She also studies morphogenesis, and how this developmental event is essential in how the nervous system functions.[5] Goodrich currently has 42 publications on research relative to the sensory system and neurobiology. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."[6] She also studies morphogenesis, and how this developmental event is essential in how the nervous system functions.[5]
Publications
She currently has 42 publications. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."[6]
Her laboratory has also created a number of resources that are made available to other researchers who have an interest in the inner ear and its development.[7]
Honors
In 1999 she was the recipient of a regional award from AAAS Science journal for her essay on “Patching together development and disease." This essay was based on her work in the department of Developmental Biology at Stanford University.[8]
References
- ^ Goodrich, Lisa. "Lisa Goodrich, PhD". Harvard University. Retrieved 20 December 2015.
- ^ "Lab Members". Goodrich Lab. Retrieved 20 December 2015.
- ^ "Research". Goodrich Lab. Retrieved 20 December 2015.
- ^ "Restoring Hearing". Action on Hearing Loss. Retrieved 20 December 2015.
- ^ a b "Resources". Goodrich Lab. Retrieved 20 December 2015.
- ^ a b "Department of Neurobiology". Harvard Medical School. Retrieved 20 December 2015.
- ^ "Lisa Goodrich". Harvard Medical School. Retrieved 20 December 2015.
- ^ "Winning Entries". sciencemag.org. American Association for the Advancement of Science. Retrieved 20 December 2015.