From Wikipedia, the free encyclopedia
TUBA1A Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3HKC , 4X20 , 3HKE , 3N2G , 4X1Y , 3N2K , 4X1I , 4X1K , 3HKB , 3HKD , 5JCO
Identifiers Aliases TUBA1A , B-ALPHA-1, LIS3, TUBA3, tubulin alpha 1aExternal IDs OMIM : 602529 ; MGI : 98869 ; HomoloGene : 68498 ; GeneCards : TUBA1A ; OMA :TUBA1A - orthologs RNA expression patternBgee Human Mouse (ortholog)Top expressed in endothelial cell ganglionic eminence inferior ganglion of vagus nerve superior vestibular nucleus spinal ganglia inferior olivary nucleus ventricular zone bronchial epithelial cell optic nerve subthalamic nucleus
Top expressed in trigeminal ganglion mammillary body medial dorsal nucleus fossa condyle medial vestibular nucleus median eminence superior cervical ganglion medial geniculate nucleus paraventricular nucleus of hypothalamus
More reference expression data
BioGPS
Wikidata
Tubulin alpha-1A chain is a protein that in humans is encoded by the TUBA1A gene .[ 5] [ 6] [ 7]
Template:PBB Summary
Interactions
TUBA1A has been shown to interact with PAFAH1B1 .[ 8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000167552 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000072235 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Crabtree DV, Ojima I, Geng X, Adler AJ (August 2001). "Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site". Bioorg Med Chem . 9 (8): 1967–76. doi :10.1016/S0968-0896(01)00103-1 . PMID 11504633 .
^ Hall JL, Cowan NJ (July 1985). "Structural features and restricted expression of a human alpha-tubulin gene" . Nucleic Acids Res . 13 (1): 207–23. doi :10.1093/nar/13.1.207 . PMC 340985 . PMID 3839072 .
^ "Entrez Gene: TUBA1A tubulin, alpha 1a" .
^ Sapir, T; Elbaum M; Reiner O (December 1997). "Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit" . EMBO J . 16 (23). ENGLAND: 6977–84. doi :10.1093/emboj/16.23.6977 . ISSN 0261-4189 . PMC 1170301 . PMID 9384577 .
Further reading
PDB gallery
1ffx : TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX
1ia0 : KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM
1jff : Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol
1sa0 : TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX
1sa1 : Tubulin-podophyllotoxin: stathmin-like domain complex
1tub : TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION
1tvk : The binding mode of epothilone A on a,b-tubulin by electron crystallography
1z2b : Tubulin-colchicine-vinblastine: stathmin-like domain complex
2hxf : KIF1A head-microtubule complex structure in amppnp-form
2hxh : KIF1A head-microtubule complex structure in adp-form
Template:PBB Controls