Talk:Naproxen

Alcohol

NSAIDs have some warning about alcohol, and I remember this being mentioned to me in person. Should we include something about alcohol and naproxen in the article? -User:Ick) 06:36, 3 September 2007 (UTC)

Absolutely. I was treated in the emergency room last night and told to take Naproxen. They told me that drinking while on the medication is quite serious and extremely dangerous. Sorry that I do not have an article citation on this; but I could tell my ER doc was quite serious about this. 24.251.84.221 02:05, 18 October 2007 (UTC)

I'm not a health professional, but I don't believe there is a direct link between the pharmacology of Naproxen (and other NSAIDs) and ethanol. The advice to avoid alcohol is because both NSAIDs and ethanol can cause stomach irritation and gastric bleeding, so ethanol may increase the prevalence and severity of these side effects. —Preceding unsigned comment added by 80.176.142.11 (talk) 19:44, 6 February 2008 (UTC)

Also a non-expert, but I think I've heard that some NSAIDs (Tylenol) have an interaction with ethanol that might lead to liver damage, whereas the others have the (fairly) mild risk of gastric upset (or more serious damage with long term use). None of that is meant to be put in the article, just a suggestion for a direction in which it might be developed, using WP:RS's. DavidOaks (talk) 13:32, 25 August 2010 (UTC)

• • Autosign signbot's statement is false and easily verified to be so from multiple, professional sites. One is to avoid more than 3 alchoholic drinks per day if using ANY NSAID. This is for an "average" person, whatever that might mean, so clearly caution makes more sense. Reasons: 1. Serious gastric or intestinal bleeding. 2. Liver damage. 3. Kidney damage. There most certainly should be a statement about alcohol in the article.

Kenfo 0 (talk) 22:12, 26 April 2011 (UTC)

There are no known hazardous interactions between Naproxen & Alcohol. NHS Website Alphaceo (talk) 17:00, 23 May 2013 (UTC)

Naprogesic

I added the trade name 'Naprogesic'. Naprogesic is a Naproxen Sodium variant sold in Australia. Not 100% sure if the trade name should be on that list, ob I don't have access to the others to rtfm. Thoughts? 220.240.227.91 09:11, 6 February 2006 (UTC)

Prescription

Could someone explain why this drug is sold as a prescription drug? As far as I can see it would have no potential for abuse..? --Javsav 10:27, 27 July 2006 (UTC)

Prescription drugs may be regulated for several reasons. Not just abuse, but safety and the seriousness of the illness they treat. I don't know specifically about Naproxen, but I can make an educated guess that it is/was a safety concern, maybe its effect on the gastrointestinal system or the possibility of interaction with other NSAIDs, which are popular over-the-counter drugs. 129.15.84.133 23:57, 31 August 2006 (UTC)

Drugs are also more likely to be sold by prescription when they are still under patent, in part because it's easier to market drugs to a comparatively small number of physicians than to the general public; in part because newer, patented prescription drugs are in some sense experimental. Clinical trials test for obvious short term negative effects, but often cannot detect rare effects (which require thousands of patients) or effects from long-term use. Such effects only become apparent after the drug has been prescribed for hundreds of thousands of patients over many years, and even then only if someone looks for an effect. Drugs that go off patent frequently become OTC (over the counter) if they are considered relatively safe, and no serious adverse effects have occurred in the years they were prescribed. Eperotao (talk) 17:14, 23 May 2008 (UTC)

Simple answer is that prescription does not mean prescription-only and over-the-counter does not mean that a drug cannot be prescribed by a doctor. This is an on-going concern to me. This is talk page so no OR or SY flagging please: as primary lay caretaker of a person prescribed Naproxen, this drug -- like all drugs -- needs to be used with the same care when it is on a written prescription Rx from a doctor or bought in the health section of a supermarket Over The Counter OTC. People prescribed hydrocodone (opioid + acetaminophen) for pain management may follow warnings not to take Tylenol but may not realize that other OTC pain relievers contain acetaminophen. Always take your Rx and OTC drugs when you visit your doctor or pharmacist and have them checked for interactions and contraindictions. For eample, OTC Tagament for upset stomach interacts with prescription Citalopram but few laypersons would realize that. People think OTC means safe (maybe by itself). I have another family member who was taken to a specialist who vetted all her Rx and OTC meds for intended use and unintended side effects and eliminated about a third of them with vast improvement in her health. --Naaman Brown (talk) 14:10, 14 September 2013 (UTC)

Stomach Cancer

This article has an unsourced statement claiming that has been linked to stomach cancer. However, Cancer.org claims it -reduces- the incidence of stomach cancer. http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_stomach_cancer_be_prevented_40.asp SailorAlea 12:06, Sep 13 2006

Citations

problem solved. --84.172.231.31 19:28, 4 March 2007 (UTC)

Naproxen Sodium tablet photograph

Naproxen tablet

CPO792 20:01, 15 May 2007 (UTC)CPO792

Adverse Effects

i think it's known that naproxen sodium can cause stevens-johnson syndrome. http://en.wikipedia.org/wiki/Stevens-Johnson_syndrome —Preceding unsigned comment added by 195.112.144.194 (talk) 08:18, 22 November 2007 (UTC)

I´m taking naproxen for a operation i have about 10 days ago, i need it to cope wiht the pain and inflamation, but i don´t know when it is nessecity or is startin to become something else, my uestion is, does Naproxen can cause adiction, or who addictive is this drug? 19:22, 25 January 2008. —Preceding unsigned comment added by 201.140.75.250 (talk)

Naproxen isn't physically addictive, none of the NSAIDs are. You should watch out for any analgesic with an opiate content (codeine, dihydrocodeine, oxycodone, methadone, morphine etc) as these certainly can result in addiction. --80.176.142.11 (talk) 19:54, 6 February 2008 (UTC)

About "addiction": It's worth distinguishing between addiction and physical dependence.Opiates cause chemical dependency in all people who take them long term, but addiction is relatively rare in pain patients who are not already addicts. Addictive behavior includes obsessive thoughts about the drug, taking more of the drug than is needed to control pain--i.e., getting high--and an inability to function well in day to day life because of abusing the drug. Chronic pain patients may cope very well, not abuse the drug (get high), and even forget to take it (as opposed to thinking obsessively about it).Eperotao (talk) 17:24, 23 May 2008 (UTC)

I'm bothered by the following sentence:

The National Institutes of Health prematurely terminated a randomized clinical trial of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested an increased risk of major cardiovascular events, such as heart attack or stroke, in patients taking naproxen.

My understanding was that it was known if these cardiovascular events were "major" or quite minor, as the data were never released. That's what I just read here at the Washington Post: <http://www.washingtonpost.com/wp-dyn/articles/A52625-2005Jan31.html> Unless, more information has come up, I would delete the word "major." Eperotao (talk) 17:24, 23 May 2008 (UTC)

I was told by the pharmacist to always eat with my Naproxen (which I take to cure a pericarditis). A work colleague told me she completely forgot her neck pain due to stomach cramps for taking Naproxen without food. I see no mention of this in the article. Maybe it should be updated? But I can't really mention personal experience as a source for the article... CielProfond (talk) 16:45, 9 December 2008 (UTC)

Naproxen

I'm due to have surgery in a few days for an arthritis issue and was wondering if Naproxen is a blood thinner and therefore wrong to take before surgery —Preceding unsigned comment added by 98.240.198.171 (talk) 03:53, 18 August 2008 (UTC)

Naproxen Sodium

I had an injury 1 year ago and I have been taking Naproxen Sodium all this time.

I take 550mg twice a day. I have gained 50lbs. and have trouble sleeping. I was finally seheduled for an epidural 2 months ago and during the check up, prior to the injection, I had my BP checked for the first time since my injury. I had no prior episodes of hypertension but during the check up it was 240/160. I went and saw a doctor about my bp and was given an alpha blocker and a diuretic which actually increased my bp. My question is, Could this be a side affect of the Naproxen? 207.69.139.145 (talk) 13:40, 28 October 2008 (UTC)

Structure and details

Naproxen is an oblong White Pill with the medical imprint code "IP110" following parallel score on the back which is for the patient using the drug can half it.

I think that description should be removed (or ammended), because not all Naproxen tablets look like that, the ones I get are blue, don't have "IP110" nor a score on it. Kyprosサマ (talk) 05:47, 18 January 2009 (UTC)

Was the discoverer of Naproxen trying to find a cure for the common cold?

I removed the sentence, "Naproxen was designed...while...trying to discover a cure for the common cold" because it wasn't supported by the source cited. However, if the part of the statement excerpted above is actually true, then it should be re-added with proper sourcing. Bwrs (talk) 16:21, 21 February 2009 (UTC)

Aleve is available in Quebec

While this press release says Aleve isn't available over-the-counter in Quebec, I can assure you that it is available "behind the counter," having bought it here in Montreal several times since mid-July. There is evidently some confusion about the exact meaning of "over-the-counter" here. The article on OTC drugs discusses "restricted OTC substances", which are drugs available without a prescription but stored behind the pharmacy counter and dispensed by the pharmacist. I would say these are still considered OTC drugs, even if they're not on the general pharmacy shelves. "Over-the-counter" is a confusing term anyway.

Further complicating things is the Aleve website, which reads "Sorry, ALEVE® is not available in BC/NFLD at this time. Coupon not valid in Quebec." Does this mean Aleve isn't available at all in B.C. and Newfoundland-Labrador? Or is it available behind the pharmacy counter? I'll be sending an email to the Bayer representative listed in the press release to ask for clarification. Puck35 (talk) 19:06, 16 August 2009 (UTC)

Aleve *is* available OTC in NL. Perhaps they obtained permission to do so after the original press release referred to in this article. I can personally confirm but can find nothing official on Bayer.ca or aleve.ca other than the coupon is valid in NL. 174.116.18.211 (talk) 21:58, 16 January 2010 (UTC)

risk of heart attack and stroke

I deleted this section because its bullshit and someone put it back in. Go read the study in source 5. Theres no statistical significance. —Preceding unsigned comment added by 98.209.40.98 (talk) 17:20, 19 November 2009 (UTC)

New data 2014 = "NAPROXEN LINKED TO HEART ATTACK RISK FOR OLDER WOMEN. Futurity (7/15) reports that a new study found that regular use of the painkiller naproxen may increase the risk of stroke, heart attack, and even death in postmenopausal women. The researchers analyzed data from more than 160,000 postmenopausal women who were surveyed as part of the Women’s Health Initiative—a 15-year research study funded by the National Institutes of Health." http://www.futurity.org/naproxen-heart-attack-women-731052/ — Preceding unsigned comment added by 128.231.237.7 (talk) 18:21, 15 July 2014 (UTC)

premature?

The article currently concludes with "The National Institutes of Health prematurely terminated a randomized clinical trial[5] of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested similar effects to Vioxx, such as heart attack or stroke, in patients taking naproxen." However, the cited source actually states "For celecoxib, ADAPT data do not show the same level of risk as those of the APC trial. The data for naproxen, although not definitive, are suggestive of increased cardiovascular and cerebrovascular risk." [emphasis added]. It seems that the WP article is over stating the case for naproxen--at least the wp claim doesn't seem to follow from the cited source. Ann arbor street (talk) 20:33, 9 January 2010 (UTC)

In combination

I am currently taking brand name Vimovo, 500mg/20mg combination of naproxen and esomeprazole. It was prescribed to me for shoulder tendinitis. I thought I might find more information about it here on Wikipedia, but it seems to be new to you. The NSAID-PPI combination drug is apparently supposed to reduce the chance of NSAID-related ulcers. It appears that Axorid is a similar brand, with different ingredients. I'd edit this article or the other, but this type of combination drug seems to warrant its own page. I'll leave it to others to decide what, if anything, to do with this. 24.57.210.141 (talk) 02:08, 30 June 2012 (UTC)

Why Sodium?

Why is it called Naproxen Sodium? The chemical formula states that there isn't actually any sodium in it. 2601:8:8900:436:8006:E424:8DA8:635D (talk) 19:30, 23 February 2014 (UTC)

This article is not about Aleve, Naprosyn etc which are Naproxen Sodium, a different drug from Naprpoxen which is not water soluable and may not be medically useful. The article is probably wrong that "Naproxen _and_ naproxen sodium are marketed under various brand names ...". Certainly the m.w. and other chemical info is wrong about the drug people actually get. 73.81.150.65 (talk) 07:56, 3 February 2017 (UTC)