LRRC8D

LRRC8D
Identifiers
Aliases	LRRC8D, LRRC5, leucine-rich repeat containing 8 family member D, leucine rich repeat containing 8 family member D, leucine rich repeat containing 8 VRAC subunit D, HsLRRC8D
External IDs	OMIM: 612890; MGI: 1922368; HomoloGene: 10004; GeneCards: LRRC8D; OMA:LRRC8D - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	89,936,611 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	105,980,302 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; subthalamic nucleus; ; trigeminal ganglion; ; external globus pallidus; ; Medulla Oblongata; ; superior vestibular nucleus; ; corpus callosum; ; ventral tegmental area; ; gingival epithelium; ; Region I of hippocampus proper;
	Top expressed in
	otolith organ; ; utricle; ; superior cervical ganglion; ; stria vascularis; ; medullary collecting duct; ; trigeminal ganglion; ; Rostral migratory stream; ; median eminence; ; cumulus cell; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; volume-sensitive anion channel activity;
Cellular component	cytoplasm; integral component of membrane; integral component of plasma membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; ion channel complex; plasma membrane;
Biological process	anion transmembrane transport; ion transport; regulation of anion transport; signal transduction; transmembrane transport; transport; cell volume homeostasis; inorganic anion transport; taurine transport; aspartate transmembrane transport; cellular response to osmotic stress;
	Sources:Amigo / QuickGO
Orthologs
	55144
	231549
	ENSG00000171492
	ENSMUSG00000046079
	Q7L1W4
	Q8BGR2
	NM_001134479; NM_018103
	NM_001122768; NM_178701
	NP_001127951; NP_060573
	NP_001116240; NP_848816
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich repeat-containing protein 8D is a protein that in humans is encoded by the LRRC8D gene.^[5] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171492 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000046079 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: LRRC8D leucine rich repeat containing 8 family, member D".

References

Further reading