ALPK1

ALPK1
Identifiers
Aliases	ALPK1, 8430410J10Rik, LAK, alpha kinase 1, ROSAH
External IDs	OMIM: 607347; MGI: 1918731; HomoloGene: 11849; GeneCards: ALPK1; OMA:ALPK1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	112,442,621 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	127,574,176 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; blood; ; pancreatic ductal cell; ; monocyte; ; Achilles tendon; ; gastric mucosa; ; spleen; ; sural nerve; ; skin of abdomen;
	Top expressed in
	granulocyte; ; ventricular zone; ; spermatid; ; esophagus; ; embryo; ; genital tubercle; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; superior frontal gyrus; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; ATP binding; kinase activity; protein serine/threonine kinase activity; protein binding; monosaccharide binding;
Cellular component	cytoplasm; cytosol;
Biological process	protein phosphorylation; phosphorylation; immune system process; cytoplasmic pattern recognition receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	80216
	71481
	ENSG00000073331
	ENSMUSG00000028028
	Q96QP1
	Q9CXB8
	NM_001102406; NM_001253884; NM_025144
	NM_027808
	NP_001095876; NP_001240813; NP_079420
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-protein kinase 1 is an enzyme that in humans is encoded by the ALPK1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000073331 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028028 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ryazanov AG, Pavur KS, Dorovkov MV (Mar 1999). "Alpha-kinases: a new class of protein kinases with a novel catalytic domain". Curr Biol. 9 (2): R43–5. doi:10.1016/S0960-9822(99)80006-2. PMID 10021370.
^ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
^ "Entrez Gene: ALPK1 alpha-kinase 1".

Human ALPK1 genome location and ALPK1 gene details page in the UCSC Genome Browser.