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Clinical trial: oral feeding with a soft diet compared with clear liquid diet as initial meal in mild acute pancreatitis.

The purpose of this primary study was to determine which method of treatment, a clear liquid diet or a soft diet, is the superior treatment to acute pancreatitis. A large sample size of 101 patients were randomly assigned to the clear liquid diet or soft diet, both following a period of fasting. The results proved a statistically significant difference in length of hospitalization. The soft diet had a median of 2 days less in the length of hospitalization as determined by a medical team unaffiliated to the study coordinators. This study suggests that oral refeeding with a soft diet, rather than a clear liquid diet, to treat mild acute pancreatitis could result in a shorter length of hospitalization.

Non‐liquid as initial meal in mild acute pancreatitis: Renewed meta‐analysis.

This secondary source, a meta-analysis of four randomized-control trials, reviewed pain recurrence and length of hospitalization when patients with acute pancreatitis were treated with a soft diet or a clear liquid diet. This meta-analysis considered large sample sizes amounting to 492 patients. Results indicated that a soft diet does not increase pain recurrence after re-feeding, as there was no significant difference in the recurrence of pain when comparing the soft diets with clear liquid diets. The length of hospitalization was reduced with a soft diet. Notably, this differs from common clinical practices after acute pancreatitis. The study warns that soft diets should not be considered the preferred diet until types, dosages, and specific regimens are identified and studied.

A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis.

In this primary study, 121 patients were randomized to a clear liquid diet or low-fat solid diet after hospitalization for mild acute pancreatitis. The observed variables included pain recurrence, need to stop feeding, and re-admission rates. There was no difference in pain or nausea between the two groups. There was also no significant difference in the length of hospitalization or re-admission rates after 28 days. The low-fat solid diet consumed significantly more calories and fat than members of the clear liquid diet group. The study concluded that oral nutrition after mild acute pancreatitis could safely be done with a low-fat solid diet.

Early use of low residue diet is superior to clear liquid diet after elective colorectal surgery. A randomized controlled trial.

The diet advancement of oral nutrition after colorectal surgery was studied as either a clear fluid diet or low residue diet, starting one day after surgery. A randomized controlled trial compared the two methods. The sample size was 111 patients. Low residue diets resulted in a significantly shorter length of hospital stay by an average of a 1.4 day decrease. There was a significant increase in mean nausea for the clear fluid diet. There was no significant difference in postoperative morbidity. The study concluded that a low residue diet, in comparison to a clear fluid diet, is associated with less nausea and a shorter hospital stay without increasing postoperative morbidity.