The team finished 2010 with a 35–5 record, becoming the ACC Regular Season Co-Champion, ACC Tournament Champion, and earning a #1 seed in the 2010 NCAA Men's Division I Basketball Tournament. The Blue Devils beat Butler in the championship game 61–59 to win the fourth national championship in school history.
*Non-conference game. #Rankings from AP. (#) Tournament seedings in parentheses. All times are in Eastern Time.[1].
Game Notes – NCAA Tournament
Second Round: Hampton
Teams
1st
2nd
Final
(16) HAMP
22
23
45
(1) DUKE
39
48
87
Duke opened the 2011 NCAA Tournament with a match up against #16 seed Hampton. Duke came out and took care of business with a commanding 39–22 lead going into halftime. As the game continued, Duke built a larger margin and easily took the first game of the tournament, beating Hampton 87–45. After Kyrie Irving suffered a toe injury in December and missed 26 games, he made his return against Hampton. After a slow start, Irving led the team in scoring with 14 points while playing 20 minutes.
Third Round: Michigan
Teams
1st
2nd
Final
(8) MICH
33
38
71
(1) DUKE
37
36
73
Duke continued their 2011 NCAA Tournament bid with a Third Round match up with the Michigan Wolverines. Duke opened the game going back and forth with Michigan, going into halftime with a 38–33 lead. However, even after leading by 15 points midway through the second half, the Wolverines would not go away. Bringing the game down to the final seconds, it was Duke who prevailed behind Nolan Smith's 24 and beat Michigan 73–71 moving them on to the Sweet Sixteen in Anaheim. This victory also gave coach Mike Krzyzewski his 900th career victory, becoming only the fourth coach to accomplish this feat.
Regional Semifinal: Arizona
Teams
1st
2nd
Final
(5) ARIZ
38
55
93
(1) DUKE
44
33
77
Duke played well in the first half and was up by 6 points at halftime. Arizona was only kept within range by a stellar performance by Wildcats forward Derrick Williams, who scored 25 of his 32 points in the first half. In the second half, Williams' teammates came alive as Arizona went on a 19–2 run from which Duke was unable to recover.