HSD17B6

HSD17B6
Identifiers
Aliases	HSD17B6, HSE, RODH, SDR9C6, hydroxysteroid (17-beta) dehydrogenase 6, hydroxysteroid 17-beta dehydrogenase 6
External IDs	OMIM: 606623; MGI: 1351670; HomoloGene: 20811; GeneCards: HSD17B6; OMA:HSD17B6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,787,790 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	127,843,480 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; lower lobe of lung; ; seminal vesicula; ; parietal pleura; ; spleen; ; canal of the cervix; ; saphenous vein; ; caudate nucleus; ; nucleus accumbens; ; prostate;
	Top expressed in
	left lobe of liver; ; duodenum; ; olfactory epithelium; ; jejunum; ; morula; ; intestinal villus; ; pyloric antrum; ; blastocyst; ; epithelium of stomach; ; mucous cell of stomach;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	electron transfer activity; oxidoreductase activity; estradiol 17-beta-dehydrogenase activity; catalytic activity; testosterone dehydrogenase (NAD+) activity; NAD-retinol dehydrogenase activity;
Cellular component	organelle membrane; endosome; early endosome membrane; intracellular anatomical structure; endoplasmic reticulum; membrane; intracellular membrane-bounded organelle;
Biological process	androgen biosynthetic process; androgen catabolic process; steroid metabolic process; lipid metabolism; electron transport chain;
	Sources:Amigo / QuickGO
Orthologs
	8630
	27400
	ENSG00000025423
	ENSMUSG00000025396
	O14756
	Q9R092
	NM_003725
	NM_013786; NM_001359377
	NP_003716
	NP_038814; NP_001346306
	Wikidata
View/Edit Human	View/Edit Mouse

Hydroxysteroid 17-beta dehydrogenase 6 is an enzyme that in humans is encoded by the HSD17B6 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000025423 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025396 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Baker ME (Feb 2001). "Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action". Mol Cell Endocrinol. 171 (1–2): 211–5. doi:10.1016/S0303-7207(00)00414-7. PMID 11165032.
^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
^ "Entrez Gene: HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)".

References

Further reading