KIAA0409

RRP8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ZFU
Identifiers
Aliases	RRP8, KIAA0409, NML, ribosomal RNA processing 8, methyltransferase, homolog (yeast), ribosomal RNA processing 8
External IDs	OMIM: 615818; MGI: 1914251; HomoloGene: 5621; GeneCards: RRP8; OMA:RRP8 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,603,616 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	105,386,592 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; right lobe of liver; ; gonad; ; mucosa of transverse colon; ; popliteal artery; ; tibial arteries; ; ventricular zone; ; granulocyte; ; body of uterus; ; right auricle;
	Top expressed in
	zygote; ; genital tubercle; ; tail of embryo; ; primitive streak; ; epiblast; ; ureter; ; embryo; ; primary oocyte; ; embryo; ; secondary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; S-adenosylmethionine-dependent methyltransferase activity; methylated histone binding; protein binding; RNA binding;
Cellular component	plasma membrane; nucleoplasm; rDNA heterochromatin; chromatin silencing complex; nucleolus; nucleus; cytosol;
Biological process	cellular response to glucose starvation; regulation of transcription, DNA-templated; regulation of transcription by glucose; transcription, DNA-templated; methylation; rDNA heterochromatin assembly; intrinsic apoptotic signaling pathway by p53 class mediator; rRNA processing; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	23378
	101867
	ENSG00000132275
	ENSMUSG00000030888
	O43159
	Q9DB85
	NM_015324
	NM_025897; NM_133951
	NP_056139
	NP_080173; NP_598712
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132275 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030888 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
^ "Entrez Gene: KIAA0409 KIAA0409".

References

Further reading