KIAA0409

RRP8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ZFU
Identifiers
Aliases	RRP8, KIAA0409, NML, ribosomal RNA processing 8, methyltransferase, homolog (yeast), ribosomal RNA processing 8
External IDs	OMIM: 615818; MGI: 1914251; HomoloGene: 5621; GeneCards: RRP8; OMA:RRP8 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,603,616 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	105,386,592 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; right lobe of liver; ; gonad; ; mucosa of transverse colon; ; popliteal artery; ; tibial arteries; ; ventricular zone; ; granulocyte; ; body of uterus; ; right auricle;
	Top expressed in
	zygote; ; genital tubercle; ; tail of embryo; ; primitive streak; ; epiblast; ; ureter; ; embryo; ; primary oocyte; ; embryo; ; secondary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; S-adenosylmethionine-dependent methyltransferase activity; methylated histone binding; protein binding; RNA binding;
Cellular component	plasma membrane; nucleoplasm; rDNA heterochromatin; chromatin silencing complex; nucleolus; nucleus; cytosol;
Biological process	cellular response to glucose starvation; regulation of transcription, DNA-templated; regulation of transcription by glucose; transcription, DNA-templated; methylation; rDNA heterochromatin assembly; intrinsic apoptotic signaling pathway by p53 class mediator; rRNA processing; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	23378
	101867
	ENSG00000132275
	ENSMUSG00000030888
	O43159
	Q9DB85
	NM_015324
	NM_025897; NM_133951
	NP_056139
	NP_080173; NP_598712
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132275 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030888 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
^ "Entrez Gene: KIAA0409 KIAA0409".

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132275 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030888 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9455477-5] Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.

[entrez-6] "Entrez Gene: KIAA0409 KIAA0409".

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References

Further reading