ADAS-Cog
The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is a brief neuropsychological assessment used to assess the severity of cognitive symptoms of dementia. It is one of the most widely used cognitive scales in clinical trials[1] and is considered to be the “gold standard” for assessing antidementia treatments.[2]
The ADAS-Cog comprises one half of the Alzheimer’s Disease Assessment Scale (ADAS), which also contains a non-cognitive subscale (ADAS-Noncog), which includes 10 tasks which assess mood and behavioural changes which may changes which may occur in Alzheimer's disease and other forms of dementia.[3]
The ADAS-Cog consist of 11 questions:
- Word Recall Task
- Naming Objects and Fingers
- Following Commands
- Constructional Praxis
- Ideational Praxis
- Orientation
- Word Recognition Task
- Remembering Test Directions
- Spoken Language
- Comprehension
- Word-Finding Difficulty
Different versions
Since it's original creation there have been several versions of the ADAS-Cog created for various. These include:
- ADAS-Cog Plus: Developed to be more responsive to the early stage deficits seen is mild cognitive impairment. It includes the standard ADAS-Cog with additional tests to assess executive function and day-to-day function.[4]
- VADAS-Cog: The VADAS-Cog is a variant the ADAS-Cog adapted to assess people with vascular dementia. It is comprised of the standard ADAS-Cog with additional measures for attention, working memory, executive function and verbal fluency.[5]
References
- ^ Connor, D. J. & Sabbagh, M. N. (2008). "Administration and Scoring Variance on the ADAS-Cog". = Journal of Alzheimer’s Disease. 15 (3): 461–464. doi:10.3233/JAD-2008-15312.
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: CS1 maint: extra punctuation (link) CS1 maint: multiple names: authors list (link) - ^ Kueper, J. K., Speechley, M., & Montero-Odasso, M. (2018). "The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Modifications and responsiveness in pre-dementia populations. A narrative review". Journal of Alzheimer’s Disease. 63 (2): 423–444. doi:10.3233/JAD-1709.
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: CS1 maint: multiple names: authors list (link) - ^ Kueper, J. K., Speechley, M., & Montero-Odasso, M. (2018). "The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Modifications and responsiveness in pre-dementia populations. A narrative review". Journal of Alzheimer’s Disease. 63 (2): 423–444. doi:10.3233/JAD-1709.
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: CS1 maint: multiple names: authors list (link) - ^ Skinner, J.,Carvalho, J. O., Guy, G. P., Thames, A., Zelinski, E., Crane, P. K., & Gibbons, L. E. (2012). "The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): An expansion of the ADAS-Cog to improve responsiveness in MCI". Brain Imaging and Behavior. 6 (4): 489–501. doi:10.1007/s11682-012-9166-3.
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: CS1 maint: multiple names: authors list (link) - ^ Ferris, S. H. (2005). "General measures of cognition". International Psychogeriatrics. 15 (S1): 215–217. doi:10.1017/S1041610203009220.