SARS-CoV-2
 | This article documents a current event. Information may change rapidly as the event progresses, and initial news reports may be unreliable. The latest updates to this article may not reflect the most current information. |
 | This article needs more reliable medical references for verification or relies too heavily on primary sources. (January 2020) |  |
| Novel coronavirus (2019-nCoV) | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | incertae sedis |
| Virus: | Novel coronavirus (2019-nCoV)
|
  | |
| Wuhan, China, the primary location of the only recorded outbreak | |
| Synonyms | |
| |
| NCBI genome ID | MN908947 |
|---|---|
| Genome size | 30473 bases |
| Year of completion | 2020 |
Novel coronavirus, denoted 2019-nCoV by the WHO[1][2] and also known as Wuhan coronavirus, Wuhan seafood market pneumonia virus and Wuhan pneumonia,[3] is a positive-sense, single-stranded RNA coronavirus first reported in 2019. The virus was genomically sequenced after nucleic acid testing on a positive patient sample in a patient with pneumonia during the 2019–2020 Wuhan pneumonia outbreak.[4][5][6]
On 20 January 2020, human-to-human transmission was confirmed in Guangdong province, China, according to Zhong Nanshan, head of the health commission team investigating the outbreak.[7] No specific treatment for the new virus is currently available, but existing anti-virals could be repurposed.[8]
The virus has spread to Bangkok, Tokyo, South Korea, Beijing, Shanghai, Guangdong Province, Taiwan, and Washington State[9] in the United States. There have been 9 fatalities and 440 known cases.[10][11][12]
Phylogenetics
Sequences of Wuhan betacoronavirus show similarities to betacoronaviruses found in bats; however, the virus is genetically distinct from other coronaviruses such as Severe acute respiratory syndrome-related coronavirus (SARS) and Middle East respiratory syndrome-related coronavirus (MERS).[6] Like SARS-CoV, it is a member of Beta-CoV lineage B.[13][14][15]
Five genomes of the novel coronavirus have been isolated and reported including BetaCoV/Wuhan/IVDC-HB-01/2019, BetaCoV/Wuhan/IVDC-HB-04/2020, BetaCoV/Wuhan/IVDC-HB-05/2019, BetaCoV/Wuhan/WIV04/2019, and BetaCoV/Wuhan/IPBCAMS-WH-01/2019 from the China CDC, Institute of Pathogen Biology, and Wuhan Jinyintan Hospital.[6][16][17] Its RNA sequence is approximately 30 kb in length.[6]
See also
Diseases caused by genetically similar viruses:
References
- ^ "Surveillance case definitions for human infection with novel coronavirus (nCoV)". www.who.int. Retrieved 21 January 2020.
- ^ "Novel coronavirus (2019-nCoV), Wuhan, China". cdc.gov. 10 January 2020. Retrieved 16 January 2020.
{{cite web}}: CS1 maint: url-status (link) - ^ Zhang, Y.-Z.; et al. (12 January 2020). "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome". GenBank. Bethesda MD. Retrieved 13 January 2020.
- ^ "中国疾病预防控制中心". www.chinacdc.cn. Retrieved 9 January 2020.
- ^ "New-type coronavirus causes pneumonia in Wuhan: expert – Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 9 January 2020.
- ^ a b c d "CoV2020". platform.gisaid.org. Retrieved 12 January 2020.
{{cite web}}: CS1 maint: url-status (link) - ^ "China confirms human-to-human transmission of new coronavirus". CBC News. 20 January 2020. Retrieved 21 January 2020.
{{cite news}}: CS1 maint: url-status (link) - ^ "WHO says new China coronavirus could spread, warns hospitals worldwide". Reuters. 14 January 2020. Retrieved 21 January 2020.
- ^ "China Virus Spreads to U.S. With Health Officials on High Alert". Bloomberg.com. 21 January 2020. Retrieved 21 January 2020.
- ^ "Wuhan virus: China reports fourth death in pneumonia outbreak; 15 medical workers infected". straitstimes. Retrieved 20 January 2020.
- ^ "CNBC: CDC confirms first US case of coronavirus that has killed 9 in China". Berkeley Lovelace Jr. Retrieved 22 January 2020.
- ^ "China virus death toll rises to nine". 9news.au. Retrieved 22 January 2020.
- ^ "Phylogeny of SARS-like betacoronaviruses". nextstrain. Retrieved 18 January 2020.
- ^ Hui DS, I Azhar E, Madani TA, Ntoumi F, Kock R, Dar O, Ippolito G, Mchugh TD, Memish ZA, Drosten C, Zumla A, Petersen E. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis. 2020 Jan 14;91:264-266. PMID 31953166 doi:10.1016/j.ijid.2020.01.009
- ^ "Wuhan virus: Number of cases soars past 400 in China, death toll rises to 9". Channelnewsasia. Retrieved 22 January 2020.
- ^ "Initial genome release of novel coronavirus". Virological. 11 January 2020. Retrieved 12 January 2020.
- ^ "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome". 17 January 2020.
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External links
Media related to SARS-CoV-2 at Wikimedia Commons
The dictionary definition of Wuhan pneumonia at Wiktionary
