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Jason Sheltzer is a cancer biology and independent fellow at Cold Spring Harbor Laboratory[1][2].
Education
Sheltzer received a BA in molecular biology from Princeton University and a PhD in biology from the Massachusetts Institute of Technology[3][4]. At MIT, Sheltzer performed his PhD research with Angelika Amon on the consequences of aneuploidy[5]. Sheltzer then established his own research group as an independent fellow at Cold Spring Harbor Laboratory[6][7].
Career and research
Sheltzer uses CRISPR/Cas9 technology to study aneuploidy and cancer genomics. Through the use of chromosome engineering, he has constructed cancer cells with different degrees of aneuploidy, and he has found how aneuploidy affects tumor suppression and metastasis[8][9]. In 2019, he discovered a set of copy number alteration biomarkers that can be used to predict cancer patient outcomes[10][11]. His research has questioned whether anti-cancer drugs could be acting through alternate mechanisms[12][13][14].
Sheltzer has also studied gender disparities in biology research. He discovered that some faculty members, like Nobel Prize winners, tended to hire very few female students in their labs, which could contribute to the gender gap in STEM[15][16][17].
Awards and honors
- National Institutes of Health, Early Independence Award[18]
- Forbes Magazine, 30 under 30 in Science[19]
- White House Office of Science and Technology, Presidential Early-Career Science and Engineering Award[20]
References
- ^ Ricks, Delthia (2018-12-25). "Researcher aims to take uncertainty out of cancer diagnosis". Newsday. Retrieved 2020-06-06.
{{cite web}}: CS1 maint: url-status (link) - ^ Zimmer, Carl (2019-09-11). "Why Aren't Cancer Drugs Better? The Targets Might Be Wrong". The New York Times. ISSN 0362-4331. Retrieved 2020-06-06.
- ^ Austin, Jim (2014-07-08). "A Young Tag Team Detects a Major Pipeline Leak". Science | AAAS. Retrieved 2020-06-06.
{{cite web}}: CS1 maint: url-status (link) - ^ "AACR-Bayer Innovation and Discovery Grants | American Association for Cancer Research". American Association for Cancer Research (AACR). Retrieved 2020-06-06.
- ^ "McKinley and Sheltzer to Receive 2016 Bernfield and Gilula Awards". ASCB. 2016-10-06. Retrieved 2020-06-06.
- ^ "Researcher aims to take uncertainty out of cancer diagnosis". Newsday. Retrieved 2020-06-06.
- ^ "AACR-Bayer Innovation and Discovery Grants | American Association for Cancer Research". American Association for Cancer Research (AACR). Retrieved 2020-06-06.
- ^ Seton-Rogers, Sarah (March 2017). "Fitness penalties of aneuploidy". Nature Reviews Cancer. 17 (3): 142–143. doi:10.1038/nrc.2017.9. ISSN 1474-1768.
- ^ Seton-Rogers, Sarah (2020-03-31). "Weighing up effects of extra chromosomes". Nature Reviews Cancer. 20 (5): 259–259. doi:10.1038/s41568-020-0257-y. ISSN 1474-175X.
- ^ "Researcher aims to take uncertainty out of cancer diagnosis". Newsday. Retrieved 2020-06-06.
- ^ "Cancer Genetic Studies Explore Prognostic Value of Copy Number Alterations, Other Biomarkers". GenomeWeb. Retrieved 2020-06-06.
- ^ Zimmer, Carl (2019-09-11). "Why Aren't Cancer Drugs Better? The Targets Might Be Wrong". The New York Times. ISSN 0362-4331. Retrieved 2020-06-06.
- ^ Belluz, Julia (2019-09-16). "Most cancer drugs fail in testing. This might be a big reason why". Vox. Retrieved 2020-06-06.
- ^ Preidt, Robert (2019-09-11). "Cancer Drugs Sometimes Work in Unexpected Ways: Study". U.S. News and World Report.
{{cite web}}: CS1 maint: url-status (link) - ^ McGregor, Jenna (2014-07-17). "Study: Top labs run by men tend to hire fewer women". The Washington Post.
{{cite news}}: CS1 maint: url-status (link) - ^ "Study: Male Scientists Employ Fewer Women in Labs". Time. Retrieved 2020-06-06.
- ^ Hu, Jane C. (2014-06-30). "Male Professors Rarely Train Female Scientists". Slate Magazine. Retrieved 2020-06-06.
- ^ "NIH Director's Early Independence Award Program - 2015 Award Recipients | NIH Common Fund". commonfund.nih.gov. Retrieved 2020-06-06.
- ^ "Jason Sheltzer, 28". Forbes. Retrieved 2020-06-06.
- ^ "President Donald J. Trump Announces Recipients of the Presidential Early Career Award for Scientists and Engineers". The White House. Retrieved 2020-06-06.