Cowdry bodies
Cowdry bodies are eosinophilic or basophilic[1] nuclear inclusions composed of nucleic acid and protein seen in cells infected with Herpes simplex virus, Varicella-zoster virus, and Cytomegalovirus. They are named after Edmund Cowdry.
There are two types of intranuclear Cowdry bodies:
- Type A (as seen in herpes simplex and VZV) [2]
- Type B (as seen in infection with poliovirus and CMV), though it may seem that this is an antiquated and perhaps illusory type.[3]
Light microscopy is used for detection of Cowdry bodies.
References
- ^ "Cytomegalovirus (CMV) colitis". www.pathologyoutlines.com. Retrieved 2019-04-11.
- ^ "Herpes Group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr)". Retrieved 2009-01-02.
- ^ "Neuropathology blog: Whither the Illusory Cowdry B Inclusion of Polio?". 13 November 2008.
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