EIF4E3

EIF4E3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4B6U, 4B6V
Identifiers
Aliases	EIF4E3, eIF-4E3, eIF4E-3, eukaryotic translation initiation factor 4E family member 3
External IDs	OMIM: 609896; MGI: 1914142; HomoloGene: 41652; GeneCards: EIF4E3; OMA:EIF4E3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	71,754,773 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	99,666,771 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tibialis anterior muscle; ; deltoid muscle; ; mucosa of ileum; ; monocyte; ; myocardium of left ventricle; ; quadriceps femoris muscle; ; gastrocnemius muscle; ; vastus lateralis muscle; ; biceps brachii;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; interventricular septum; ; Rostral migratory stream; ; brown adipose tissue; ; triceps brachii muscle; ; temporal muscle; ; myocardium of ventricle; ; vastus lateralis muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	translation initiation factor activity; RNA binding; RNA 7-methylguanosine cap binding;
Cellular component	cytoplasm; cytosol; mRNA cap binding complex; eukaryotic translation initiation factor 4F complex;
Biological process	translational initiation; regulation of translation; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	317649
	66892
	ENSG00000163412
	ENSMUSG00000093661
	Q8N5X7
	Q9DBB5
	NM_001134649; NM_001134650; NM_001134651; NM_001282886; NM_173359
	NM_025829
	NP_001128121; NP_001128122; NP_001128123; NP_001269815; NP_775495
	NP_080105
	Wikidata
View/Edit Human	View/Edit Mouse

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Eukaryotic translation initiation factor 4E family member 3 is a protein that in humans is encoded by the EIF4E3 gene.^[5]

EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163412 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000093661 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Eukaryotic translation initiation factor 4E family member 3". Retrieved 2011-09-28.
^ Joshi B, Cameron A, Jagus R (June 2004). "Characterization of mammalian eIF4E-family members". European Journal of Biochemistry. 271 (11): 2189–2203. doi:10.1111/j.1432-1033.2004.04149.x. PMID 15153109.

External links

Overview of all the structural information available in the PDB for UniProt: Q9DBB5 (Mouse Eukaryotic translation initiation factor 4E type 3) at the PDBe-KB.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163412 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000093661 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Eukaryotic translation initiation factor 4E family member 3". Retrieved 2011-09-28.

[6] Joshi B, Cameron A, Jagus R (June 2004). "Characterization of mammalian eIF4E-family members". European Journal of Biochemistry. 271 (11): 2189–2203. doi:10.1111/j.1432-1033.2004.04149.x. PMID 15153109.

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