File:Complete androgen insensitivity syndrome.jpg

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Summary

Non-free media information and use rationale true for Complete androgen insensitivity syndrome
Description	Women with complete androgen insensitivity are born phenotypically female, despite having a 46,XY karyotype.
Source	Left, Simpson JL. Disorders of Sexual Differentiation: Etiology and Clinical Delineation. New York: Academic Press, 1976. Right, Gilbert SF. Developmental biology, sixth edition. Sunderland, MA: Sinauer Associates, 2000. Photos by Charles B. Hammond, Duke University.
Article	Complete androgen insensitivity syndrome
Portion used	Single image from an article in a medical journal.
Low resolution?	The resolution is necessary for readers to be able to properly appreciate the fully female appearance of women with CAIS. The resolution of this image will not affect journal subscriptions (i.e. revenue).
Purpose of use	This image illustrates that women with complete androgen insensitivity are phenotypically normal women, and that the Y chromosome does not affect the femininity of their bodies.
Replaceable?	CAIS is a rare disorder, affecting approximately 1 in 20,000 births. It is worthy to note that this subject is sensitive, and calls for medical quality photography.
Other information	Sources that describe CAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:) Banksboll S, Qvist I, Lebech PE et al. Testicular feminization syndrome and associated gonadal tumours in Denmark. Acta Obstetricia et Gynecologica Scandinavica 1992;71:63-66. (3:) Hughes I, Deeb A. Androgen resistance. Best Pract Res Clin Endocrinol Metab. 2006;20:577-598.
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File history

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	20:24, 22 August 2018		353 × 470 (79 KB)	AlyInWikiWonderland (talk \| contribs)	Better cropping, no white spacing in the middle.
	00:29, 20 September 2010	No thumbnail	379 × 470 (88 KB)	Jonathan.Marcus (talk \| contribs)	{{Non-free use rationale \|Article = Androgen insensitivity syndrome \|Description = Women with complete androgen insensitivity are born phenotypically female, despite having a 46,XY karyotype. \|Source = ''Left,'' Simpson JL. '

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Complete androgen insensitivity syndrome