File:Intramolecular cyclization of cis-rotamer.svg
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Original file (SVG file, nominally 512 × 437 pixels, file size: 28 KB)
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Summary
| Description |
English: Here is shown the conversion of the trans-rotamer to cis-rotamer, which undergoes intramolecular cyclization, losing enzyme-inhibiting activity. This problem occurred during the development of DPP-4 inhibitors vildagliptin and saxagliptin. Created with ChemDoodle 7.0.2 and Adobe Illustrator CC 2015. |
| Date | |
| Source | Own work |
| Author | Vaccinationist |
W3C-validity not checked.
Licensing
|
This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship. |  |
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 11:51, 10 November 2016 | | 512 × 437 (28 KB) | Vaccinationist | fonts |
| 12:32, 10 July 2015 |  | 512 × 436 (39 KB) | Vaccinationist | changed some parts to emphasize cyclization | |
| 12:21, 10 July 2015 |  | 512 × 436 (39 KB) | Vaccinationist | User created page with UploadWizard |
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