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伏妥昔单抗：修订间差异

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'''伏妥昔单抗'''（INN：futuximab，开发代号：'''992 DS'''）是一种嵌合单克隆抗体，设计用于治疗癌症。<ref>[http://www.ama-assn.org/resources/doc/usan/x-pub/futuximab.pdf Statement On A Nonproprietary Name Adopted By The USAN Council - Futuximab], ''[[American Medical Association]]''.</ref>它充当免疫调节剂并与 HER1 结合。<ref>{{cite journal | author = [[World Health Organization]] | title = International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 | journal = WHO Drug Information | volume = 26 | issue = 2 | year = 2012 | url =https://www.who.int/medicines/publications/druginformation/innlists/Final_PL107.pdf }}</ref><ref>{{cite journal |vauthors=Keir ST, Chandramohan V, Hemphill CD, Grandal MM, Melander MC, Pedersen MW, Horak ID, Kragh M, Desjardins A, Friedman HS, Bigner DD |title=Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models |journal=J. Neurooncol. |volume=138 |issue=3 |pages=489–498 |date=July 2018 |pmid=29564747 |doi=10.1007/s11060-018-2832-6 |pmc=5999169 }}</ref>
'''伏妥昔单抗'''（[[INN]]：futuximab，开发代号：'''992 DS'''），或译'''夫妥昔单抗'''、'''福妥昔单抗'''，是一种嵌合[[单克隆抗体]]，设计用于治疗[[癌症]]。<ref>[http://www.ama-assn.org/resources/doc/usan/x-pub/futuximab.pdf Statement On A Nonproprietary Name Adopted By The USAN Council - Futuximab] {{Wayback|url=http://www.ama-assn.org/resources/doc/usan/x-pub/futuximab.pdf |date=20160402051807 }}, ''[[American Medical Association]]''.</ref>它充当[[免疫调节剂]]并与[[HER1]]结合。<ref>{{cite journal | author = [[World Health Organization]] | title = International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 | journal = WHO Drug Information | volume = 26 | issue = 2 | year = 2012 | url = https://www.who.int/medicines/publications/druginformation/innlists/Final_PL107.pdf | access-date = 2024-03-06 | archive-date = 2016-03-04 | archive-url = https://web.archive.org/web/20160304063336/http://www.who.int/medicines/publications/druginformation/innlists/Final_PL107.pdf | dead-url = no }}</ref><ref>{{cite journal |vauthors=Keir ST, Chandramohan V, Hemphill CD, Grandal MM, Melander MC, Pedersen MW, Horak ID, Kragh M, Desjardins A, Friedman HS, Bigner DD |title=Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models |journal=J. Neurooncol. |volume=138 |issue=3 |pages=489–498 |date=July 2018 |pmid=29564747 |doi=10.1007/s11060-018-2832-6 |pmc=5999169 }}</ref>


该药物由[[Symphogen]]开发。
该药物由{{le|Symphogen|Symphogen}}开发。


== 参考资料 ==
== 参考资料 ==

2024年6月20日 (四) 12:39的最新版本

伏妥昔单抗
单克隆抗体
种类完整抗体
目標HER1
臨床資料
其他名稱992 DS
ATC碼
  • 未分配
识别信息
CAS号1310460-85-5
ChemSpider
  • none
UNII
化学信息
化学式C6468H10002N1724O2055S46
摩尔质量146,269.94 g·mol−1

伏妥昔单抗（INN：futuximab，开发代号：992 DS），或译夫妥昔单抗、福妥昔单抗，是一种嵌合单克隆抗体，设计用于治疗癌症。[1]它充当免疫调节剂并与HER1结合。[2][3]

该药物由Symphogen（英语：Symphogen）开发。

参考资料

[编辑]
  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Futuximab （页面存档备份，存于互联网档案馆）, American Medical Association.
  2. ^ World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 (PDF). WHO Drug Information. 2012, 26 (2) [2024-03-06]. （原始内容存档 (PDF)于2016-03-04）. 
  3. ^ Keir ST, Chandramohan V, Hemphill CD, Grandal MM, Melander MC, Pedersen MW, Horak ID, Kragh M, Desjardins A, Friedman HS, Bigner DD. Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models. J. Neurooncol. July 2018, 138 (3): 489–498. PMC 5999169 可免费查阅. PMID 29564747. doi:10.1007/s11060-018-2832-6. 
检索自“https://zh.wikipedia.org/zhwiki/w/index.php?title=伏妥昔单抗&oldid=83108594”