醇脫氫酶：修订间差异
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==外部連結== |
==外部連結== |
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{{commons category|Alcohol dehydrogenase}} |
{{commons category|Alcohol dehydrogenase}} |
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* [http://www.biochem.ucl.ac.uk/bsm/enzymes/ec1/ec01/ec01/ec0001/index.html PDBsum] has links to three-dimensional structures of various alcohol dehydrogenases contained in the [[Protein Data Bank]] |
* [https://web.archive.org/web/20080517055711/http://www.biochem.ucl.ac.uk/bsm/enzymes/ec1/ec01/ec01/ec0001/index.html PDBsum] has links to three-dimensional structures of various alcohol dehydrogenases contained in the [[Protein Data Bank]] |
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* [http://www.expasy.org/cgi-bin/nicezyme.pl?1.1.1.1 ExPASy] contains links to the alcohol dehydrogenase sequences in [[Swiss-Prot]], to a [[Medline]] literature search about the enzyme, and to entries in other databases. |
* [http://www.expasy.org/cgi-bin/nicezyme.pl?1.1.1.1 ExPASy] contains links to the alcohol dehydrogenase sequences in [[Swiss-Prot]], to a [[Medline]] literature search about the enzyme, and to entries in other databases. |
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2018年9月25日 (二) 04:36的版本
| 醇脱氢酶 | |||||||||
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| 人源ADH5二聚体的蛋白质晶体结构[1] | |||||||||
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| 识别码 | |||||||||
| EC編號 | 1.1.1.1 | ||||||||
| CAS号 | 9031-72-5 | ||||||||
| 数据库 | |||||||||
| IntEnz | IntEnz浏览 | ||||||||
| BRENDA | BRENDA入口 | ||||||||
| ExPASy | NiceZyme浏览 | ||||||||
| KEGG | KEGG入口 | ||||||||
| MetaCyc | 代谢路径 | ||||||||
| PRIAM | 概述 | ||||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 基因本体 | AmiGO / EGO | ||||||||
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醇脫氫酶（英語：Alcohol dehydrogenase，縮寫ALDH， EC 1.1.1.1），是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下两种酶促反应：
醇脱氢酶是一种锌蛋白，能作用于伯醇、仲醇和半缩醛等多种受質。这种酶氧化甲醇的能力比氧化乙醇的能力弱，可以利用這個特性解除甲醇中毒。动物细胞中的醇脱氢酶还能氧化环状化合物的二级羟基，但酵母的醇脱氢则不具有这种功能。
參考
- ^ PDB 1m6h; Sanghani PC, Robinson H, Bosron WF, Hurley TD. Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes. Biochemistry. September 2002, 41 (35): 10778–86. PMID 12196016. doi:10.1021/bi0257639.
外部連結
- PDBsum has links to three-dimensional structures of various alcohol dehydrogenases contained in the Protein Data Bank
- ExPASy contains links to the alcohol dehydrogenase sequences in Swiss-Prot, to a Medline literature search about the enzyme, and to entries in other databases.
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