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C5a受体:修订间差异

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*肝癌细胞[[Hep G2]]以及由其衍生的肝癌细胞系
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==另见==
==另见==

2021年3月5日 (五) 23:44的版本

C5a受体
識別號
别名C5AR1;, C5A, C5AR, C5R1, CD88, complement component 5a receptor 1, C5a receptor, complement C5a receptor 1
外部IDOMIM113995 MGI88232 HomoloGene20413 GeneCardsC5AR1
基因位置(人类
19號染色體
染色体19號染色體[1]
19號染色體
C5a受体的基因位置
C5a受体的基因位置
基因座19q13.32起始47,290,023 bp[1]
终止47,322,066 bp[1]
RNA表达模式
查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_001736

NM_001173550
​NM_007577

蛋白序列

NP_001727

NP_001167021
​NP_031603

基因位置​(UCSC)Chr 19: 47.29 – 47.32 MbChr 7: 15.98 – 15.99 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

C5a受体(英語:C5a receptor或称补体成分5a受体1,complement component 5a receptor 1C5AR1CD88Cluster of Differentiation 88)是一种与补体C5a英语Complement component 5a相结合的G蛋白偶联受体[5]

C5a受体结构及其与配体结合信号转导相关的氨基酸残基

细胞

C5a受体表达于以下细胞:[6]

另见

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000197405 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000049130 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Gerard C, Gerard NP. C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu. Rev. Immunol. 1994, 12: 775–808. PMID 8011297. doi:10.1146/annurev.iy.12.040194.004015. 
  6. ^ Klos A, Wende E, Wareham KJ, Monk PN. International Union of Pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol. Rev. 2013, 65 (1): 500–43. PMID 23383423. doi:10.1124/pr.111.005223. 

延伸阅读

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  • Bao L, Gerard NP, Eddy RL; et al. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19.. Genomics. 1992, 13 (2): 437–40. PMID 1612600. doi:10.1016/0888-7543(92)90265-T. 
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