培那西林：修订间差异

培那西林
臨床資料
AHFS/Drugs.com	国际药品名称
ATC碼	J01CE06 (WHO) ;
识别信息
	IUPAC命名法 (acetyloxy)methyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; ;
CAS号	983-85-7
PubChem CID	13795;
ChemSpider	8426255 ;
UNII	H0P1YE5581;
KEGG	D05406 ;
ChEBI	CHEBI:131733 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID10243547 ;
ECHA InfoCard	100.012.338
化学信息
化学式	C19H22N2O6S
摩尔质量	406.45 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CC(=O)OCOC(=O)[C@H]1C(S[C@H]2N1C(=O)[C@H]2NC(=O)CC3=CC=CC=C3)(C)C;
	InChI InChI=1S/C19H22N2O6S/c1-11(22)26-10-27-18(25)15-19(2,3)28-17-14(16(24)21(15)17)20-13(23)9-12-7-5-4-6-8-12/h4-8,14-15,17H,9-10H2,1-3H3,(H,20,23)/t14-,15+,17-/m1/s1 ; Key:NLOOMWLTUVBWAW-HLLBOEOZSA-N ;

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2023年3月25日 (六) 03:07的最新版本

培那西林（英语：Penamecillin）是苄青霉素的乙酰氧基甲酯，是一种通过酯酶加工成苄青霉素的前体药物。^[1]

一项研究表明，怀孕期间口服培那西林治疗未对胎儿造成可检测的致畸风险。^[2]

参考资料

^ Agersborg HP, Batchelor A, Cambridge GW, Rule AW. The pharmacology of penamecillin. British Journal of Pharmacology and Chemotherapy. March 1966, 26 (3): 649–55. PMC 1510697 . PMID 4959939. doi:10.1111/j.1476-5381.1966.tb01844.x.
^ Andrew Czeizel. 青霉素V的安全性：妊娠期间口服培那西林的使用召回偏差的重要性和局限性 The Safety of Penicillin V: Oral Penamecillin Use During Pregnancy The Importance and Limitation of Recall Bias. [2023-03-01]. （原始内容存档于2023-03-01）（英语）.

[1] Agersborg HP, Batchelor A, Cambridge GW, Rule AW. The pharmacology of penamecillin. British Journal of Pharmacology and Chemotherapy. March 1966, 26 (3): 649–55. PMC 1510697 . PMID 4959939. doi:10.1111/j.1476-5381.1966.tb01844.x.

[2] Andrew Czeizel. 青霉素V的安全性：妊娠期间口服培那西林的使用召回偏差的重要性和局限性 The Safety of Penicillin V: Oral Penamecillin Use During Pregnancy The Importance and Limitation of Recall Bias. [2023-03-01]. （原始内容存档于2023-03-01）（英语）.

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@@ 第6行： / 第6行： @@
 '''培那西林'''（英语：Penamecillin）是[[苄青霉素]]的乙酰氧基甲酯，是一种通过[[酯酶]]加工成苄青霉素的[[前体药物]]。<ref>{{cite journal |vauthors=Agersborg HP, Batchelor A, Cambridge GW, Rule AW |date=March 1966 |title=The pharmacology of penamecillin |journal=British Journal of Pharmacology and Chemotherapy |volume=26 |issue=3 |pages=649–55 |doi=10.1111/j.1476-5381.1966.tb01844.x |pmc=1510697 |pmid=4959939}}</ref>
-一项研究表明，[[怀孕]]期间口服培那西林治疗未对[[胎儿]]造成可检测的致畸风险。<ref>{{Cite web|author=Andrew Czeizel|first=|title=青霉素V的安全性：妊娠期间口服培那西林的使用召回偏差的重要性和局限性|script-title=The Safety of Penicillin V: Oral Penamecillin Use During Pregnancy The Importance and Limitation of Recall Bias|url=https://www.researchgate.net/publication/229684862_The_Safety_of_Penicillin_V_Oral_Penamecillin_Use_During_Pregnancy_The_Importance_and_Limitation_of_Recall_Bias|language=en}}</ref>
+一项研究表明，[[怀孕]]期间口服培那西林治疗未对[[胎儿]]造成可检测的致畸风险。<ref>{{Cite web|author=Andrew Czeizel|first=|title=青霉素V的安全性：妊娠期间口服培那西林的使用召回偏差的重要性和局限性|script-title=The Safety of Penicillin V: Oral Penamecillin Use During Pregnancy The Importance and Limitation of Recall Bias|url=https://www.researchgate.net/publication/229684862_The_Safety_of_Penicillin_V_Oral_Penamecillin_Use_During_Pregnancy_The_Importance_and_Limitation_of_Recall_Bias|language=en|access-date=2023-03-01|archive-date=2023-03-01|archive-url=https://web.archive.org/web/20230301085311/https://www.researchgate.net/publication/229684862_The_Safety_of_Penicillin_V_Oral_Penamecillin_Use_During_Pregnancy_The_Importance_and_Limitation_of_Recall_Bias|dead-url=no}}</ref>
 == 参考资料 ==