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ICBP43

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维基百科，自由的百科全书

这是本页的一个历史版本，由Htmlzycq（留言 | 贡献）在2024年2月3日 (六) 04:47 （→HR+）编辑。这可能和当前版本存在着巨大的差异。

ICBP43是43种人类乳腺癌细胞系的列表[1]，由国家癌症研究所的“癌症生物学综合计划”（Integrative Cancer Biology Program）列出[2]，用于药物筛选等许多生物医学研究[3]。

细胞系

三阴性乳腺癌

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
BT-20 66.15h Basal HTB-19 [4] CVCL_0178
MDA-MB-231 Claudin-low HTB-26 [5] CVCL_0062
MDA-MB-468 Basal HTB-132 [6] CVCL_0419
Hs 578T Claudin-low HTB-126 [7] CVCL_0332
BT-549 Claudin-low HTB-122 [8] CVCL_1092
184B5 Basal CRL-8799 [9] CVCL_4688
DU4475
HCC38
HCC70
HCC1187
HCC1395
HCC1599
HCC1806
HCC1937
HCC2157
MDA-MB-157
MDA-MB-436
MDA-MB-453

HR+

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
MCF-7 25.4h Luminal HTB-22 [10] CVCL_0031
T-47D 45.5h Luminal HTB-133 [11] CVCL_0553
BT-483 Luminal HTB-121 [12] CVCL_2319
CAMA-1
HCC1428
HCC1500
MDA-MB-134-VI
MDA-MB-175-VII
MDA-MB-415
ZR-75-1 Luminal CRL-1504 [13] CVCL_0588

HER2amp

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
SK-BR-3 HTB-30 [14] CVCL_0033
AU565 [15] CVCL_1074
BT-474 [16] CVCL_0179
HCC202
HCC1419
HCC1569
HCC1954
HCC2218
MDA-MB-361
UACC-812
UACC-893
ZR-75-30 CRL-1504

NM

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
MCF-10A 26.74h Non-malignant Basal CRL-10317 [17] CVCL_0598
MCF-10F 47.44h Non-malignant Basal CRL-10318 [17] CVCL_3633
MCF-12A 35.42h Non-malignant Basal CRL-10782 [18] CVCL_3744

另见

参考文献

  1. ^ ICBP43 cell lines - HMS LINCS Project. lincs.hms.harvard.edu. 
  2. ^ Reagents - HMS LINCS Project. lincs.hms.harvard.edu. 
  3. ^ Anderson, Alexander R. A.; Tomlin, Claire J.; Couch, Jennifer; Gallahan, Dan. Mathematics of the Integrative Cancer Biology Program. Interface Focus. 2013-08-06, 3 (4): 20130023. doi:10.1098/RSFS.2013.0023. 
  4. ^ Chavez, KJ; Garimella, SV; Lipkowitz, S. Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer.. Breast disease. 2010, 32 (1-2): 35–48 [2019-12-04]. PMID 21778573. doi:10.3233/BD-2010-0307. 
  5. ^ Cailleau, R; Young, R; Olivé, M; Reeves WJ, Jr. Breast tumor cell lines from pleural effusions.. Journal of the National Cancer Institute. 1974-09, 53 (3): 661–74. PMID 4412247. doi:10.1093/jnci/53.3.661. 
  6. ^ Cailleau, R; Olivé, M; Cruciger, QV. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization.. In vitro. 1978-11, 14 (11): 911–5 [2020-02-14]. PMID 730202. doi:10.1007/bf02616120. （原始内容存档于2020-02-14）. 
  7. ^ Hackett, AJ; Smith, HS; Springer, EL; Owens, RB; Nelson-Rees, WA; Riggs, JL; Gardner, MB. Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines.. Journal of the National Cancer Institute. 1977-06, 58 (6): 1795–806. PMID 864756. doi:10.1093/jnci/58.6.1795. 
  8. ^ Lasfargues, EY; Coutinho, WG; Redfield, ES. Isolation of two human tumor epithelial cell lines from solid breast carcinomas.. Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）. 
  9. ^ Stampfer, MR; Bartley, JC. Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.. Proceedings of the National Academy of Sciences of the United States of America. 1985-04, 82 (8): 2394–8. PMID 3857588. doi:10.1073/pnas.82.8.2394. 
  10. ^ Lee, Adrian V.; et al. MCF-7 Cells—Changing the Course of Breast Cancer Research and Care for 45 Years. Journal of the National Cancer Institute. 1 July 2015, 107 (7): djv073. PMID 25828948. doi:10.1093/jnci/djv073. 
  11. ^ Yu, S; Kim, T; Yoo, KH; Kang, K. The T47D cell line is an ideal experimental model to elucidate the progesterone-specific effects of a luminal A subtype of breast cancer.. Biochemical and biophysical research communications. 2017-05-06, 486 (3): 752–758 [2019-11-30]. PMID 28342866. doi:10.1016/j.bbrc.2017.03.114. 
  12. ^ Lasfargues, EY; Coutinho, WG; Redfield, ES. Isolation of two human tumor epithelial cell lines from solid breast carcinomas.. Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）. 
  13. ^ Dorssers, LC; van Agthoven, T. Genetic mechanisms of estrogen-independence in breast cancer.. Pathology, research and practice. 1996-07, 192 (7): 743–51 [2019-11-28]. PMID 8880875. doi:10.1016/S0344-0338(96)80096-3. 
  14. ^ SK-BR-3: Human Breast Cancer Cell Line (ATCC HTB-30). Memorial Sloan-Kettering Cancer Center. [2018-06-18]. （原始内容存档于2018-06-18）. 
  15. ^ Bacus, SS; Kiguchi, K; Chin, D; King, CR; Huberman, E. Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen.. Molecular carcinogenesis. 1990, 3 (6): 350–62 [2019-12-04]. PMID 1980588. doi:10.1002/mc.2940030607. 
  16. ^ Lasfargues, EY; Coutinho, WG; Dion, AS. A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication.. In vitro. 1979-09, 15 (9): 723–9 [2019-12-07]. PMID 94035. doi:10.1007/bf02618252. 
  17. ^ 17.0 17.1 Soule, HD; Maloney, TM; Wolman, SR; Peterson WD, Jr; Brenz, R; McGrath, CM; Russo, J; Pauley, RJ; Jones, RF; Brooks, SC. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10.. Cancer research. 1990-09-15, 50 (18): 6075–86. PMID 1975513. 
  18. ^ Neve, RM; Chin, K; Fridlyand, J; Yeh, J; Baehner, FL; Fevr, T; Clark, L; Bayani, N; Coppe, JP; Tong, F; Speed, T; Spellman, PT; DeVries, S; Lapuk, A; Wang, NJ; Kuo, WL; Stilwell, JL; Pinkel, D; Albertson, DG; Waldman, FM; McCormick, F; Dickson, RB; Johnson, MD; Lippman, M; Ethier, S; Gazdar, A; Gray, JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.. Cancer cell. 2006-12, 10 (6): 515–27. PMID 17157791. doi:10.1016/j.ccr.2006.10.008. 
检索自“https://zh.wikipedia.org/zhwiki/w/index.php?title=ICBP43&oldid=80776644”