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ICBP43

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维基百科，自由的百科全书

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ICBP43是43种人类乳腺癌细胞系的列表[1]，由美国国家癌症研究所的“癌症生物学综合计划”（Integrative Cancer Biology Program）列出[2]，用于药物筛选等许多生物医学研究[3]。

细胞系

三阴性乳腺癌

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
BT-20 66.15h Basal HTB-19 [4] CVCL_0178
MDA-MB-231 41.9h Claudin-low HTB-26 [5] CVCL_0062
MDA-MB-468 62h Basal HTB-132 [6] CVCL_0419
Hs 578T 53.8h Claudin-low HTB-126 [7] CVCL_0332
BT-549 53.9h Claudin-low HTB-122 [8] CVCL_1092
184B5 56.15h Basal CRL-8799 [9] CVCL_4688
DU4475 90h ？ HTB-123 [10] CVCL_1183
HCC38 50.98h Claudin-low CRL-2314 [11] CVCL_1267
HCC70 67.80h Basal CRL-2315 [11] CVCL_1270
HCC1187 69.35h Basal CRL-2322 [11] CVCL_1247
HCC1395 84.07h Claudin-low CRL-2324 [11] CVCL_1349
HCC1599 4-5d Basal CRL-2331 [11] CVCL_1256
HCC1806 36.66h Basal CRL-2335 [11] CVCL_1258
HCC1937 53.49h Basal CRL-2336 [11] CVCL_0290
HCC2157 ？ ？ CRL-2340 [11] CVCL_1261
MDA-MB-157 Claudin-low HTB-24 [6]
MDA-MB-436 Claudin-low HTB-130 [6]
MDA-MB-453 62.49h Luminal HTB-131 [12] CVCL_0418

HR+

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
MCF-7 25.4h Luminal HTB-22 [13] CVCL_0031
T-47D 45.5h Luminal HTB-133 [14] CVCL_0553
BT-483 140.00h Luminal HTB-121 [15] CVCL_2319
CAMA-1 72.94h Luminal HTB-21 [16] CVCL_1115
HCC1428 88.48h Luminal CRL-2327 [11] CVCL_1252
HCC1500 46.85h ？ CRL-2329 [11] CVCL_1254
MDA-MB-134-VI Luminal HTB-23 [6]
MDA-MB-175-VII Luminal HTB-25 [6]
MDA-MB-415 Luminal HTB-128 [6]
ZR-75-1 70.09h Luminal CRL-1504 [17] CVCL_0588

HER2amp

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
SK-BR-3 56.19h HER2+ HTB-30 [18] CVCL_0033
AU565 46.31h HER2+ CRL-2351 [19] CVCL_1074
BT-474 92.49h HER2+ HTB-20 [20] CVCL_0179
HCC202 212.49h HER2+ CRL-2316 [11] CVCL_2062
HCC1419 161.42h HER2+ CRL-2326 [11] CVCL_1251
HCC1569 45.43h ？ CRL-2330 [11] CVCL_1255
HCC1954 43.81h HER2+ CRL-2338 [11] CVCL_1259
HCC2218 120h HER2+ CRL-2343 [11] CVCL_1263
MDA-MB-361 92.83h HER2+ HTB-27 [6] CVCL_0620
UACC-812 HER2+ CRL-1897
UACC-893 Luminal CRL-1902
ZR-75-30 324.46h Luminal CRL-1504 [21] CVCL_1661

NM

细胞系 倍增时间 转录亚型 ATCC ID 文献 外部链接
MCF-10A 26.74h Non-malignant Basal CRL-10317 [22] CVCL_0598
MCF-10F 47.44h Non-malignant Basal CRL-10318 [22] CVCL_3633
MCF-12A 35.42h Non-malignant Basal CRL-10782 [23] CVCL_3744

另见

参考文献

  1. ^ ICBP43 cell lines - HMS LINCS Project. lincs.hms.harvard.edu. 
  2. ^ Reagents - HMS LINCS Project. lincs.hms.harvard.edu. 
  3. ^ Anderson, Alexander R. A.; Tomlin, Claire J.; Couch, Jennifer; Gallahan, Dan. Mathematics of the Integrative Cancer Biology Program. Interface Focus. 2013-08-06, 3 (4): 20130023. doi:10.1098/RSFS.2013.0023. 
  4. ^ Chavez, KJ; Garimella, SV; Lipkowitz, S. Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer.. Breast disease. 2010, 32 (1-2): 35–48 [2019-12-04]. PMID 21778573. doi:10.3233/BD-2010-0307. 
  5. ^ Cailleau, R; Young, R; Olivé, M; Reeves WJ, Jr. Breast tumor cell lines from pleural effusions.. Journal of the National Cancer Institute. 1974-09, 53 (3): 661–74. PMID 4412247. doi:10.1093/jnci/53.3.661. 
  6. ^ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 Cailleau, R; Olivé, M; Cruciger, QV. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization.. In vitro. 1978-11, 14 (11): 911–5 [2020-02-14]. PMID 730202. doi:10.1007/bf02616120. （原始内容存档于2020-02-14）. 
  7. ^ Hackett, AJ; Smith, HS; Springer, EL; Owens, RB; Nelson-Rees, WA; Riggs, JL; Gardner, MB. Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines.. Journal of the National Cancer Institute. 1977-06, 58 (6): 1795–806. PMID 864756. doi:10.1093/jnci/58.6.1795. 
  8. ^ Lasfargues, EY; Coutinho, WG; Redfield, ES. Isolation of two human tumor epithelial cell lines from solid breast carcinomas.. Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）. 
  9. ^ Stampfer, MR; Bartley, JC. Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.. Proceedings of the National Academy of Sciences of the United States of America. 1985-04, 82 (8): 2394–8. PMID 3857588. doi:10.1073/pnas.82.8.2394. 
  10. ^ Langlois, AJ; Holder WD, Jr; Iglehart, JD; Nelson-Rees, WA; Wells SA, Jr; Bolognesi, DP. Morphological and biochemical properties of a new human breast cancer cell line.. Cancer research. 1979-07, 39 (7 Pt 1): 2604–13. PMID 221108. 
  11. ^ 11.00 11.01 11.02 11.03 11.04 11.05 11.06 11.07 11.08 11.09 11.10 11.11 11.12 11.13 11.14 Gazdar, AF; Kurvari, V; Virmani, A; Gollahon, L; Sakaguchi, M; Westerfield, M; Kodagoda, D; Stasny, V; Cunningham, HT; Wistuba, II; Tomlinson, G; Tonk, V; Ashfaq, R; Leitch, AM; Minna, JD; Shay, JW. Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.. International journal of cancer. 1998-12-09, 78 (6): 766–74. PMID 9833771. doi:10.1002/(sici)1097-0215(19981209)78:6<766::aid-ijc15>3.0.co;2-l. 
  12. ^ Hall, RE; Birrell, SN; Tilley, WD; Sutherland, RL. MDA-MB-453, an androgen-responsive human breast carcinoma cell line with high level androgen receptor expression.. European journal of cancer (Oxford, England : 1990). 1994, 30A (4): 484–90 [2020-02-14]. PMID 8018407. doi:10.1016/0959-8049(94)90424-3. [永久失效連結]
  13. ^ Lee, Adrian V.; et al. MCF-7 Cells—Changing the Course of Breast Cancer Research and Care for 45 Years. Journal of the National Cancer Institute. 1 July 2015, 107 (7): djv073. PMID 25828948. doi:10.1093/jnci/djv073. 
  14. ^ Yu, S; Kim, T; Yoo, KH; Kang, K. The T47D cell line is an ideal experimental model to elucidate the progesterone-specific effects of a luminal A subtype of breast cancer.. Biochemical and biophysical research communications. 2017-05-06, 486 (3): 752–758 [2019-11-30]. PMID 28342866. doi:10.1016/j.bbrc.2017.03.114. 
  15. ^ Lasfargues, EY; Coutinho, WG; Redfield, ES. Isolation of two human tumor epithelial cell lines from solid breast carcinomas.. Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）. 
  16. ^ Kerbel, RS; Pross, HF; Leibovitz, A. Analysis of established human carcinoma cell lines for lymphoreticular-associated membrane receptors.. International journal of cancer. 1977-11-15, 20 (5): 673–9. PMID 924690. doi:10.1002/ijc.2910200505. 
  17. ^ Dorssers, LC; van Agthoven, T. Genetic mechanisms of estrogen-independence in breast cancer.. Pathology, research and practice. 1996-07, 192 (7): 743–51 [2019-11-28]. PMID 8880875. doi:10.1016/S0344-0338(96)80096-3. 
  18. ^ SK-BR-3: Human Breast Cancer Cell Line (ATCC HTB-30). Memorial Sloan-Kettering Cancer Center. [2018-06-18]. （原始内容存档于2018-06-18）. 
  19. ^ Bacus, SS; Kiguchi, K; Chin, D; King, CR; Huberman, E. Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen.. Molecular carcinogenesis. 1990, 3 (6): 350–62 [2019-12-04]. PMID 1980588. doi:10.1002/mc.2940030607. 
  20. ^ Lasfargues, EY; Coutinho, WG; Dion, AS. A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication.. In vitro. 1979-09, 15 (9): 723–9 [2019-12-07]. PMID 94035. doi:10.1007/bf02618252. 
  21. ^ Engel, LW; Young, NA; Tralka, TS; Lippman, ME; O'Brien, SJ; Joyce, MJ. Establishment and characterization of three new continuous cell lines derived from human breast carcinomas.. Cancer research. 1978-10, 38 (10): 3352–64. PMID 688225. 
  22. ^ 22.0 22.1 Soule, HD; Maloney, TM; Wolman, SR; Peterson WD, Jr; Brenz, R; McGrath, CM; Russo, J; Pauley, RJ; Jones, RF; Brooks, SC. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10.. Cancer research. 1990-09-15, 50 (18): 6075–86. PMID 1975513. 
  23. ^ Neve, RM; Chin, K; Fridlyand, J; Yeh, J; Baehner, FL; Fevr, T; Clark, L; Bayani, N; Coppe, JP; Tong, F; Speed, T; Spellman, PT; DeVries, S; Lapuk, A; Wang, NJ; Kuo, WL; Stilwell, JL; Pinkel, D; Albertson, DG; Waldman, FM; McCormick, F; Dickson, RB; Johnson, MD; Lippman, M; Ethier, S; Gazdar, A; Gray, JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.. Cancer cell. 2006-12, 10 (6): 515–27. PMID 17157791. doi:10.1016/j.ccr.2006.10.008. 
检索自“https://zh.wikipedia.org/zhwiki/w/index.php?title=ICBP43&oldid=80828059”